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research Studies on the persistence of estradiol benzoate and nortestosterone decanoate in hair of cattle following treatment with growth promoters, determined by ultra-high-performance liquid chromatography–tandem mass spectrometry

18 citations , April 2009 in “Journal of Chromatography A”

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

High-Performance Liquid Chromatographic Determination of the Enantiomers of the Benzoquinolinone LY 191704, a Human Type 1 5α-Reductase Inhibitor, in Plasma

research High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY 191704, a human type 1 5α-reductase inhibitor, in plasma

1 citations , March 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

research Social media for arthritis-related comparative effectiveness and safety research and the impact of direct-to-consumer advertising

20 citations , March 2017 in “Arthritis research & therapy”

Social media can help compare the effectiveness and safety of new arthritis medications.

research Impact of Reporter Type on Signal Detection of Cancer Therapy-Induced Alopecia: A Hypothesis-Generating Study Using the FDA Adverse Event Reporting System

March 2026 in “Pharmaceuticals”

Reporter characteristics affect detection of hair loss from cancer therapy.

Optimization and Characterization of a Focal Dermal Hypoplasia Mouse Model to Test Potential Treatments

research 1465 Optimization/characterization of a Focal Dermal Hypoplasia mouse model to test potential treatments

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

research Machine Learning--Enhanced Pharmacovigilance Assessment of Cardiac Adverse Events Associated With Minoxidil

February 2026

Minoxidil is strongly linked to heart problems, and machine learning can improve drug safety checks.

research The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research^*

88 citations , July 2009 in “Experimental and Clinical Endocrinology & Diabetes”

research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened

March 2023

The treatment was ineffective in humans.

Selective and Rapid Determination of Tadalafil and Finasteride Using Solid Phase Extraction by High Performance Liquid Chromatography and Tandem Mass Spectrometry

research Selective and rapid determination of tadalafil and finasteride using solid phase extraction by high performance liquid chromatography and tandem mass spectrometry

9 citations , February 2018 in “Journal of Pharmaceutical and Biomedical Analysis”

Quick, selective detection of tadalafil and finasteride in human plasma developed.

research Alteration of neonatal Allopregnanolone levels affects exploration, anxiety, aversive learning and adult behavioural response to intrahippocampal neurosteroids

24 citations , December 2012 in “Behavioural Brain Research”

Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.

research NTP Toxicology and Carcinogenesis Studies of C.I. Acid Orange 3 (CAS No. 6373-74-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

2 citations , December 1988 in “PubMed”

C.I. Acid Orange 3 caused cancer in female rats but not in male rats or mice.

Production of Ultraviolet-Light-Induced Skin Erythema in the Hairless Rat: A Comparison with the Haired Rat in Screening for Anti-Inflammatory Drugs

research Production of ultraviolet-light-induced skin erythema in the hairless rat: a comparison with the haired rat in screening for anti-inflammatory drugs

3 citations , October 1979 in “Laboratory animals”

Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.

research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1

35 citations , October 2004 in “Biology of Reproduction”

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

A Simple Decision Tree for Identifying Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation

research A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation

November 2020 in “Journal of Pharmaceutical Sciences”

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Multicentric Parallel Phase II Trial of the Polo-Like Kinase 1 Inhibitor BI 2536 in Patients With Advanced Head and Neck Cancer, Breast Cancer, Ovarian Cancer, Soft Tissue Sarcoma, and Melanoma. The First Protocol of the European Organization for Research and Treatment of Cancer Network of Core Institutes

research Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)

93 citations , May 2010 in “European Journal of Cancer”

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

research 112 Post-Finasteride Syndrome – Outcomes of FDA Database

April 2016 in “The Journal of Sexual Medicine”

research Low‐dose oral minoxidil in alopecia: evaluating blood pressure changes in patients with abnormal blood pressure—a retrospective study

January 2025 in “International Journal of Dermatology”

research A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus)

1 citations , August 2024 in “GeroScience”

research 1093 Clinical effects of dutasteride and finasteride: Are they different or equivalent? Results from record-linkage and match-paired analyses

March 2013 in “European Urology Supplements”

research Cutaneous toxicity as a predictive biomarker for clinical outcome in patients receiving anticancer therapy

32 citations , May 2018 in “Journal of the American Academy of Dermatology”

Skin reactions from cancer treatments might predict how well the treatments work.

research [Determination of finasteride in human plasma by HPLC-MS].

2 citations , June 2003 in “PubMed”

The two finasteride formulations are bioequivalent.

research Subjects with mild alopecia benefit from aminexil clinical 5: results of a large international observational study

1 citations , January 2020 in “IRIS UNIMORE (University of Modena and Reggio Emilia)”

Aminexil clinical 5 effectively reduces hair loss and is well-tolerated.

research Induction and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine

3 citations , March 1981 in “Journal of Toxicology and Environmental Health”

Rats developed lung issues from the drugs, but these cleared quickly after stopping them.

research Evaluation of noninvasive biospecimens for transcriptome studies

9 citations , December 2023 in “BMC Genomics”

Hair follicles and urine cell pellets are promising for transcriptome studies.

research Nongenotoxicity of minoxidil in murine hair follicles as determined by the nuclear aberration assay

12 citations , January 1988 in “Toxicology and Applied Pharmacology”

Minoxidil promotes hair growth without causing DNA damage.

A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia

research A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetic, Pharmacodynamic, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia

June 2024 in “Advances in therapy”

IVL3001 is safe, effective, and better than oral finasteride for treating hair loss.

research LB1048 Effectiveness of OR-101 in a murine model of atopic dermatitis

July 2024 in “Journal of Investigative Dermatology”

OR101 may effectively treat atopic dermatitis and similar skin conditions.

research Evaluation of noninvasive biospecimens for transcriptome studies

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Hair follicles and urine cell pellets are promising for transcriptome studies due to consistent quality and useful expression profiles.

research 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin causes an increase in protein kinases growth hepatic associated with epidermal factor receptor in the plasma membrane

60 citations , December 1988 in “Journal of Biochemical Toxicology”

TCDD reduces EGF receptors in the liver, affecting growth and development.

research Safety, tolerability, and PK of topical calcitriol formulation for treatment of chemotherapy-induced alopecia (CIA) in patients receiving taxane-based regimen: Final results.

May 2019 in “Journal of clinical oncology”

Topical calcitriol was safe and well-tolerated for potential hair loss prevention in chemotherapy patients.

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