63 citations
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April 2017 in “Acta psychiatrica Scandinavica” Higher prenatal and adult androgen levels are linked to alcohol dependence and withdrawal severity.
Androgens reduce macrophage receptor expression, affecting immune response, while antiandrogens counteract this effect.
1 citations
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December 1992 in “International Journal of Dermatology” No significant hormone differences found in postmenopausal women with androgenetic alopecia.
8 citations
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March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
1 citations
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January 2013 in “UNICA IRIS Institutional Research Information System (University of Cagliari)” Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.
8 citations
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June 2023 in “European Journal of Endocrinology” The inhibitor affects androgen metabolism but not ovarian function.
April 2026 in “International Journal of Impotence Research” Anabolic steroid abuse can cause sexual, fertility, and health problems.
30 citations
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March 1980 in “European Journal of Endocrinology” Adrenal androgens are important for puberty and are influenced by genetics.
Cyproterone slightly inhibited hair growth in castrated mice, while tamoxifen significantly inhibited hair growth in castrated mice but not in normal mice.
5 citations
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February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
44 citations
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February 2009 in “Pain” Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
1 citations
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January 2020 in “Bioscience Reports” Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
24 citations
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July 1980 in “Journal of Toxicology and Environmental Health” High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
3 citations
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January 2021 in “Andrology” Low androgen levels reduce nitric oxide production in rat penile cells.
100 citations
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September 2017 in “Molecular and Cellular Endocrinology” Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
22 citations
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November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” Certain fats in the blood are linked to an increased risk of male pattern baldness.
December 1976 in “PubMed” Androgens affect skin conditions like acne and hirsutism, treatable with hormone therapy and other methods.
123 citations
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May 2020 in “Drug Development Research” Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
46 citations
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October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
October 2023 in “Toxicology and Applied Pharmacology” Finasteride is more harmful to male reproductive health than minoxidil.
7 citations
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August 2010 in “Medicinal Chemistry Research” Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
March 2017 in “European Urology Supplements” Gene differences affect finasteride side effects in men with hair loss.
5 citations
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July 1994 in “PubMed” Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
93 citations
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January 2000 in “Annals of Medicine” Mutations in the androgen receptor gene cause various disorders.
15 citations
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June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
October 2019 in “European heart journal” Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
7 citations
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January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
25 citations
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January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.