research Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism?
Reduced AR gene methylation may cause early pubic hair growth in girls.
Search
for
Sort by
Research
690-720 / 1000+ results research Steroid inhibitors of androgen-potentiated actions on skin
Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.
research Current understanding of androgenetic alopecia. Part I: etiopathogenesis.
Androgenetic alopecia is common hair loss due to genetics and DHT.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
research Re: Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring
Inhibiting 5α-reductase during late pregnancy shortens gestation, reduces litter size, and harms memory in rat offspring.
research Effects of anabolic-androgenic steroids on the pilosebaceous unit.
Anabolic-androgenic steroids can cause skin issues like acne and oily skin by enlarging oil glands and changing skin oils.
research The role of mutations on gene AR, in androgenetic alopecia syndrome
Mutations in the AR gene cause hair thinning and loss.
research Differences in the mechanisms of androgen action in hair follicles from women and men with androgenetic alopecia
research Faculty Opinions recommendation of Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.
Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
research Faculty Opinions recommendation of Androgen receptor gene polymorphisms and risk for androgenetic alopecia: a meta-analysis.
Certain gene variations are significantly linked to hair loss, especially in white people.
research Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS
Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.
research Early post-natal neuroactive steroid manipulation modulates ondansetron effects on initial periods of alcohol consumption in rats
Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
research DUTASTERIDE AS AN EFFECTIVE TREATMENT IN ANDROGENETIC ALOPECIA – A LITERATURE REVIEW
Dutasteride is more effective than finasteride for hair loss, but more research is needed on safety and dosing.
research A Novel Androgen Receptor Gene Mutation in a 46,XY Patient: Complete Androgen Insensitivity Syndrome
A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Significance of the polyglutamine tract polymorphism in the androgen receptor
The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.
A point mutation in the androgen receptor gene causes complete androgen insensitivity.
research Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families
No clear link between specific gene and hair loss in Mexican brothers.
research Finasteride reduces the preventive effect of uroselective α1A-blockers against cancellous bone disorders induced by androgen deficiency in rats
Finasteride weakens the bone-protective effects of certain blockers in low androgen conditions.
research Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Urinary Androgens Provide Additional Evidence Related to Metabolism and Are Correlated With Serum Androgens in Girls
The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
research Evidence for two independent functional variants for androgenetic alopecia around the androgen receptor gene
Two gene areas linked to male pattern baldness found, more research needed.
research Поняття міжкультурної комунікації та порівняльна характеристика німецької та української культур (на матеріалі німецької мови)
Low-dose effects in rodent studies are hard to confirm due to confounding factors and control group variability.
research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research Topical Testosterone Induces Acne Pilosebaceous Alterations on Rat Skin
Topical testosterone can cause acne-like skin changes.
research Male hormonal contraception: looking back and moving forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Impact of 5-alpha Reductase Inhibitors on Male Reproductive Health: A Review of Finasteride and Dutasteride.
Finasteride and dutasteride can harm male reproductive health, affecting sperm and causing sexual dysfunction.
research Enzymology of the hair follicle.
Hair follicles convert androgens, affecting hair loss patterns.
research Aspects of Cutaneous Androgen‐Dependent Syndromes
Understanding hormones is key to treating certain skin conditions.