Key genes for mink fur have been identified, aiding conservation efforts.
9 citations
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July 2008 in “Archives of Dermatological Research” The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.
December 1991 in “Annals of the New York Academy of Sciences” Keratin proteins are crucial for hair structure and strength.
53 citations
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September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
1 citations
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January 2016 in “Frontiers in Bioengineering and Biotechnology” Human hair keratin is a promising and sustainable biomaterial for tissue regeneration.
100 citations
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December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
2 citations
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August 2013 in “Journal of Investigative Dermatology” Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
88 citations
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June 2000 in “Journal of Investigative Dermatology” Keratin 17 is important for hair and nail structure and affects pachyonychia congenita symptoms.
8 citations
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June 2009 in “British Journal of Dermatology” Human melanocytes in skin and hair follicles don't express keratin 16 or 6 naturally.
November 2020 in “Research Square (Research Square)” Keratin injections in mice can stimulate hair growth and might help treat hair loss.
198 citations
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March 1999 in “Journal of Investigative Dermatology” Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
4 citations
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November 1968 in “Textile research journal” Hair fibers may have a unique, non-protein sheath not previously identified.
38 citations
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November 1991 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Keratins 8 and 14 can help identify and diagnose benign skin tumors.
19 citations
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April 1999 in “British Journal of Dermatology” Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.
128 citations
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February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
27 citations
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April 2004 in “Biochemical and Biophysical Research Communications” Two new gene clusters important for hair formation were found on human chromosome 11.
79 citations
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June 1993 in “Molecular and Cellular Biology” The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.
3 citations
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September 2013 in “Bioscience Biotechnology and Biochemistry” Type II porcine hair keratin supports cell growth but hinders cell differentiation.
133 citations
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June 1993 in “Molecular and Cellular Biology” The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.
19 citations
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March 1961 in “Nature” A fatty acid/protein complex in human hair helps protect it from damage.
26 citations
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June 2010 in “Electrophoresis” New techniques helped identify rare wool proteins by reducing dominant ones.
22 citations
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August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
1 citations
,
January 1992 in “DNA sequence” Researchers found a non-functional sheep keratin gene due to mutations.
January 1991 in “Acta Dermato Venereologica” A new method effectively visualizes keratin in hair without harsh chemicals.
4 citations
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January 2015 in “Sen'i Gakkaishi” Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.
Trichohyalin, a protein from pig tongue, was purified and found to have a filamentous structure.
11 citations
,
November 2021 in “ACS applied nano materials” Keratin-associated protein nanoparticles from human hair may help stop bleeding quickly and safely.
77 citations
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March 2000 in “Journal of Investigative Dermatology” The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.
254 citations
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January 2007 in “Chemical Society Reviews” Hair is a complex protein fiber with unique properties useful for developing hair products.