20 citations
,
June 1995 in “Tetrahedron Letters” New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
29 citations
,
February 2016 in “Scandinavian journal of urology” Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
53 citations
,
June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.
7 citations
,
September 2014 in “European Journal of Dermatology” Thicker hair grows faster; hair loss patients have slower growth.
November 2012 in “The Journal of Urology” Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.
June 2024 in “Al- Anbar Medical Journal” Acute telogen effluvium can be resolved by addressing causes, but chronic telogen effluvium is harder to treat.
8 citations
,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
5 citations
,
February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
2 citations
,
October 2015 in “Primary Care: Clinics in Office Practice” Doctors should diagnose hair loss by examining the patient and possibly doing tests, and then treat it based on the type, which may prevent permanent hair loss.
7 citations
,
August 2010 in “Medicinal Chemistry Research” Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
July 2025 in “Clinical Cosmetic and Investigational Dermatology” PRP therapy effectively improves hair density and reduces hair loss in androgenetic alopecia.
5 citations
,
July 2021 in “medRxiv (Cold Spring Harbor Laboratory)” Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.
5 citations
,
May 1994 in “Facial plastic surgery clinics of North America” Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
29 citations
,
July 2012 in “Fertility and Sterility” Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
12 citations
,
June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
6 citations
,
August 2013 in “한국응용생명화학회지” Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
6 citations
,
March 2003 in “Archiv Der Pharmazie” Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.
18 citations
,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
5 citations
,
January 2019 in “Clinical Drug Investigation” Some off-label treatments increase hair density, but long-term safety unknown.
2 citations
,
June 2020 in “BMC Health Services Research” Health warnings and public health actions led to a significant drop in flutamide prescriptions for women, but off-label use still continues.
166 citations
,
April 2012 in “Journal of The American Academy of Dermatology” Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
23 citations
,
June 2018 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) is a low-risk treatment for Androgenic Alopecia (AGA) that generally improves hair count or density, but more research is needed for optimization.
19 citations
,
March 2010 in “Bioorganic & Medicinal Chemistry Letters” Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
8 citations
,
June 1995 in “Helvetica Chimica Acta” Compound 15a was effective in inhibiting 5α-reductase.
51 citations
,
February 2010 in “Analytical and Bioanalytical Chemistry” Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
49 citations
,
August 2009 in “British Journal of Cancer” Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.
36 citations
,
August 2017 in “Journal of Cosmetic Dermatology” PRP with microneedling effectively treats hair loss, and dermoscopy helps evaluate results.