3 citations
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January 2015 in “Clinical and Experimental Dermatology” A man developed a serious muscle breakdown condition after using a hair loss medication not known to cause this side effect.
7 citations
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October 2022 in “Advances in Therapy” Current treatments for Alopecia Areata are unsatisfactory and need improvement.
October 2015 in “Elsevier eBooks” Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
166 citations
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April 2012 in “Journal of The American Academy of Dermatology” Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
143 citations
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August 1991 in “Endocrinology” Androgens, like testosterone, are crucial for early testicular descent in rats.
81 citations
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February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
69 citations
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July 2015 in “Pharmacotherapy” Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
64 citations
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March 2006 in “Food Chemistry” The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
54 citations
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April 2020 in “Experimental & Molecular Medicine” Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
52 citations
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January 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
32 citations
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March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
32 citations
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November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
28 citations
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September 2008 in “Current Pharmaceutical Design” Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.
16 citations
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January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
15 citations
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July 1991 in “International Journal of Dermatology” Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.
12 citations
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
10 citations
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June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
3 citations
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January 2018 in “Journal of South Asian Federation of Obstetrics and Gynaecology” Letrozole is better for single follicle development and endometrial thickness in PCOS, with no significant difference in pregnancy rates compared to clomiphene.
3 citations
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January 2015 in “Case reports in psychiatry” Sertraline can cause hair loss, which stops after stopping the drug.
January 2025 in “Advances in Dermatology and Allergology” A holistic approach, including medical treatments, lifestyle changes, and mental health support, is crucial for managing hirsutism in women.
Melanocytes can regenerate around hair follicles in bullous pemphigoid, especially in patients with darker skin.
Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
3 citations
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September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
173 citations
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May 2001 in “Human reproduction update” Oestrogens are key for bone growth during puberty in both boys and girls.
75 citations
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March 1999 in “Fertility and sterility” Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
50 citations
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May 2000 in “Fertility and Sterility” Flutamide reduces hair growth better but has more side effects.
16 citations
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June 2008 in “Springer eBooks” Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
15 citations
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April 2008 in “Steroids” The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.