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A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.

Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.

Certain drugs that block specific enzymes can help treat prostate diseases.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Testosterone reduces knee movement, while flutamide and finasteride increase it.

Early NAS level changes affect alcohol consumption vulnerability.

GD-23 reduces anxiety by relying on neurosteroid production.

Dutasteride works better than finasteride for hair loss and has mild, reversible side effects.

Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Finasteride reduces hair loss by blocking testosterone's effects on scalp cells.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Testosterone's muscle-building effects do not require its conversion to DHT.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Testosterone needs to be converted to DHT to reduce stress response in male rats.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Finasteride may improve prostate cancer therapy by enhancing testosterone's benefits and reducing risks.

Dutasteride is the most effective for hair loss but may cause sexual and mental side effects.