research DIABETE E DOLORE: EFFETTO TERAPEUTICO DEI METABOLITI DEL TESTOSTERONE
Testosterone metabolites may help relieve diabetic nerve pain.
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research Adverse Effects of 5-Alpha-Reductase Inhibitors: a narrative review
5-Alpha-Reductase Inhibitors can cause negative side effects.
research Crystal Structure and Synthesis of 17α-Acetoxy-4-bromopregn-4-ene-3,20-dione
The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.
research TOPICAL STEROIDS
Use mild topical steroids to avoid side effects, especially in children.
research Minoxidil, finasteride, and dutasteride
Minoxidil, finasteride, and dutasteride are treatments for hair loss.
research Low-dose naltrexone: a novel adjunctive treatment in symptomatic alopecias?
Low-dose naltrexone might be a cheap and effective additional treatment for hair loss with scalp discomfort due to its anti-inflammatory effects and few side effects.
research Classification scale for male and female androgenetic alopecia.
Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.
research Cardiovascular Toxicities of Androgen Deprivation Therapy
ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.
research Attenzione divisa nei pazienti con cerebrolesione acquisita
Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
research Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat
DHT is needed for long-term depression, while E2 is needed for full long-term potentiation in male rat brains.
research Rapid nongenomic modulation by neurosteroids of dendritic spines in the hippocampus: Androgen, oestrogen and corticosteroid
Sex and stress steroids quickly change brain cell structures in the hippocampus.
research Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study
Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.
research New Synthesis of Finasteride
A new method to make Finasteride is more cost-effective and yields 16%.
research The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses
Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
research History as a Tool in Identifying “New” Old Drugs
Finasteride, originally for prostate issues, also treats hair loss, similar to effects from certain plants.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
research Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review
Some plant-based products might treat hair loss with fewer side effects than current medications.
research Cyproterone/finasteride
Cyproterone and finasteride reduced hypersexuality but caused serious side effects.
research Compatibility of 17-α-Estradiol, Betamethasone, Finasteride, Melatonin, Prednicarbate, and Spironolactone in TrichoFoam™ - a Foaming Vehicle for Personalized Alopecia Treatments.
TrichoFoam™ effectively delivers multiple hair loss treatments, maintaining their stability and effectiveness.
research Pre-receptor regulation of the androgen receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research In vitro [7-3H]-testosterone metabolism by the rat ventral prostate—Effect of some exogenous compounds
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor
New hybrid compound found to effectively prevent hair loss.
research 198 Dutasteride for men with androgenic alopecia unresponsive to finasteride
research Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
The method effectively measures drug impact on DHT levels in prostate treatments.
research Nonclassic adrenal hyperplasia
Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.
research ANTIANDROGEN THERAPY IN DERMATOLOGY
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE
Finasteride's molecular properties and active sites were identified using computational methods.