research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
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research A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia
The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research The Hair Follicle
Dogs could be good models for studying human hair growth and hair loss.
research Platelet-Rich Plasma and Stem Cells for Hair Growth: A Review of the Literature
Platelet-Rich Plasma and stem cell therapy can increase hair count and density, but the best method for preparation and treatment still needs to be determined.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
research Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids
The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
research Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
research Wnt Signaling and Injury Repair
Wnt signaling helps heal injuries and could lead to new treatments.
research More than one way to skin . . .
Skin stem cells help repair damage and maintain healthy skin.
research Alopecia areata: a review of disease pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research Epigenetic control of adult stem cell function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Diverse mechanisms for endogenous regeneration and repair in mammalian organs
Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
research Macrophages Regulate Schwann Cell Maturation after Nerve Injury
Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
research Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation
Adult fibroblasts help heart cells mature and improve heart function.
research MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research What causes hidradenitis suppurativa ?—15 years after
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research Stem cells and the circadian clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome (PCOS): A Six-Month, Open-Label Randomized Study
Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research Prolactin—a novel neuroendocrine regulator of human keratin expressionin situ
Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
research Modulating hair follicle size with W nt10b/DKK 1 during hair regeneration
Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
research Finasteride for female androgenetic alopecia
Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
research Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Functional hair follicle regeneration: an updated review
Hair follicle regeneration possible, more research needed.
research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
research The bright side of fibroblasts: molecular signature and regenerative cues in major organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Alopecia Areata. Current situation and perspectives
Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration
TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.