research Cutaneous Drug Delivery: An Update
New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
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600-630 / 1000+ results research LB1007 Systemic treatment with a KLK5 inhibitor shows efficacy in a murine model of Netherton syndrome
A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.
research New frontiers in CRISPR/Cas9 delivery systems delivery for gene editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research Targeting telomeric RNA quadruplexes with natural metabolites to prevent cancer
research Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers - A Review
New cancer treatments aim to reduce side effects and improve effectiveness.
research Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway
Platelet-derived extracellular vesicles can boost hair growth by activating a specific signaling pathway.
research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
N-WASP is essential for healthy skin and preventing inflammation.
research Exosomes: A New Effective Non-Surgical Therapy for Androgenetic Alopecia?
Exosome therapy shows promise for hair growth without side effects but needs more testing.
research Nanozyme-loaded needles spur hair regrowth
Scientists have created a patch filled with tiny enzymes that can treat hair loss and regrow hair as effectively as common hair-loss drugs, but with fewer applications.
research Ultrasound-Assisted Facile Synthesis and Anticancer Evaluation of Novel N-(2-substituted phenyl-4-oxathiazolidine-3-carbonothioyl) benzamide
Researchers made new compounds that could potentially be developed into anticancer drugs.
research Hypoxia-preconditioned ADSC exosomes encapsulated in a multifunctional dual-network hydrogel promote the healing and functional regeneration of seawater-immersed wounds
The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Topical Application of Bio-Pulsed Avian MSC-Derived Extracellular Vesicles Enhances Hair Regrowth and Skin Rejuvenation: Evidence from Clinical Evaluation and miRNA Profiling
Bio-Pulsed sEVs improve hair growth and skin rejuvenation.
research The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration
400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
research Mesenchymal stem cell-derived exosomes ameliorate gentamicin-induced vestibular hair cell injury by regulating the SNARE pathway and enhancing autophagy
Stem cell-derived exosomes can help repair ear damage and improve balance and hearing.
research Emerging drugs and combination strategies for basal cell carcinoma
New treatments for a type of skin cancer show promise but have side effects and may work better with other therapies.
research ISX9 loaded thermoresponsive nanoparticles for hair follicle regrowth
The new treatment using nanoparticles with ISX9 can effectively regrow hair without major side effects.
research Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia
A new treatment for hair loss uses tiny lipid carriers to deliver a mix of minoxidil and latanoprost directly to hair follicles, promoting hair growth and being well tolerated by the skin.
research Human placental mesenchymal stromal cell‐derived exosome‐enriched extracellular vesicles for chronic cutaneous graft‐versus‐host disease: A case report
Exosome-enriched vesicles from placental cells improved skin condition in a patient with chronic graft-versus-host disease.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research A Mosaic Hotspot PLCD1 Variant, Detectable in Blood‐Derived DNA , Associated With Nevus Trichilemmocysticus
A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.
research 057 Single cell RNA and TCR sequencing reveals hyperexpansion of T cell clones and novel regulatory mechanisms of CD8+ T cells in murine alopcecia areata skin and draining lymph nodes
research Design and synthesis of potential nano-carrier for delivery of diphencyprone to hair follicle
research Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition
Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
research 1113 Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils via Ly6 antigen for psoriasiform dermatitis alleviation
The study created special nanoparticles that effectively deliver an anti-inflammatory drug to treat skin inflammation in psoriasis.
research Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process
Nanoparticles can effectively treat diseases by modifying blood vessel growth.
research Geleneksel Derleme: Dermatoloji ve Kozmetolojide Eksozomlar
Exosomes show promise for treating skin conditions and improving cosmetic skin health.
research Revolutionizing psoriasis care: Microneedle innovations in treatment and diagnosis
Microneedles offer a promising, less invasive way to treat and monitor psoriasis.
research Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration
Stem cell-derived organoids can improve skin healing.
research Exosomes derived stem cells as a modern therapeutic approach for skin rejuvenation and hair regrowth
Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.