research Protein degradation: expanding the toolbox to restrain cancer drug resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
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810-840 / 1000+ results research Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery
research Characterization of Novel Cutaneous Human Papillomavirus Genotypes HPV-150 and HPV-151
HPV-150 and HPV-151 are rare skin viruses linked to warts and some skin cancers.
research Acid phosphatase distribution in the wool follicle. III. Fate of organelles in keratinized cells
Keratinized wool cells still have some organelles like lysosomes and mitochondria.
research Viremia and viruria of trichodysplasia spinulosa‐associated polyomavirus before the development of clinical disease in a kidney transplant recipient
The virus linked to a rare disease was found in a patient's blood and urine before skin symptoms appeared.
research Novel diagnostic tools and markers for inflammatory skin diseases
A new test using NOS2 and CCL27 genes can better diagnose and treat psoriasis and eczema.
research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications
Nanocarriers can improve drug delivery through the skin by overcoming barriers.
research Biomembrane-Based Nanostructure- and Microstructure-Loaded Hydrogels for Promoting Chronic Wound Healing
Biomembrane-based hydrogels can effectively promote chronic wound healing.
research Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research ГНОТОБИОНТЫ – ЭКСПЕРИМЕНТАЛЬНАЯ МОДЕЛЬ
Controlled microflora in animals delays immune cell maturation and affects immunity.
research Transdermal delivery of mixnoxidil with block copolymer nanoparticles
Smaller nanoparticles improve minoxidil delivery through hair follicles.
research Human dermal fibroblast‐derived secretory proteins for regulating nerve restoration: A bioinformatic approach
Human dermal fibroblast proteins help restore nerves during healing.
research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin
Topical oligonucleotide therapy targets hair follicles effectively.
research A case of MBTPS1 ‐related disorder due to compound heterozygous variants in MBTPS1 gene: Genotype–phenotype expansion and the emergence of a novel syndrome
A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.
research 568 Novel synthetic melanin nanoparticles improve skin wound healing
research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
research Sesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.
research Netherton Syndrome: A Case-Based Review of Diagnosis, Management, and Emerging Treatments.
Early genetic testing and new therapies like secukinumab are crucial for managing Netherton syndrome effectively.
research PULMONARY DELIVERY OF RESVERATROL-LOADED NANOCOMPOSITE MICROPARTICLES TO TREAT LUNG CANCER
Resveratrol-loaded nanoparticles show promise for lung cancer treatment.
research Self-Amplifying RNA Approach for Protein Replacement Therapy
Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
research Application of stem cells in regeneration medicine
Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.
research Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia
Curcumin-primed milk vesicles may help treat hair loss by promoting hair growth.
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research A local drug delivery system based on visible light-cured glycol chitosan and doxorubicin⋅hydrochloride for thyroid cancer treatment in vitro and in vivo
GC10/DOX hydrogel shows promise as an effective thyroid cancer treatment.
research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling
Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
research Recent Advances in Polymer Microneedles for Drug Transdermal Delivery: Design Strategies and Applications
Polymer microneedles are a promising, painless alternative to traditional needles for delivering drugs through the skin.
research Electron Microscope Studies of the Human Epidermis The Clear Cell of Masson (Dendritic Cell or Melanocyte)
A unique skin cell similar to hair bulb melanocytes was identified, with better preservation using permanganate fixation.
research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning
Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
research Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche
Low fucosylation boosts stem cell growth in the eye.
research Ανάπτυξη καινοτόμων πεπτιδικών φορέων με ιδιότητες αυτοσυναρμογής για τοπική χορήγηση φαρμάκων
Self-assembling peptide hydrogels effectively deliver drugs locally, enhancing treatment and reducing side effects.