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Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

KID syndrome should be reclassified as an ectodermal dysplasia.

Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

The combination therapy is effective and well-tolerated for treating esophageal cancer.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

The new formulation improved the skin absorption of the drug Thiocolchicoside.

MPA increases cancer spread by boosting Eph A2 activity.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

An 11-year-old Greek girl was diagnosed with a rare genetic disorder, highlighting the importance of genetic testing and family history.

Dermal EZH2 controls skin cell development and hair growth in mice.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

Comprehensive genetic testing and international collaboration are crucial for better understanding and managing Ehlers-Danlos syndromes.

Dacomitinib can cause nail and skin issues, but these can be managed without stopping the drug.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.

Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

CCCA may involve the PD1/PDL1 pathway and increased caspase 3, leading to permanent hair loss.

Touch dome keratinocytes in adult skin have traits of different skin cell types.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.

Nephronectin is linked to worse outcomes in breast cancer and helps cancer spread.

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

A severe form of Netherton syndrome caused by a specific gene mutation led to neonatal deaths in a family.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

A new genetic mutation was found causing hair and eye issues in a boy.

A form of vitamin E promotes hair growth by activating a specific skin pathway.

Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.