research The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse
Disrupted stem cell signals in hairpoor mice cause hair loss.
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research Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation
Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.
research Neuroprotective and immunomodulatory effects of human hair follicle stem cells on streptozotocin-induced memory impairment in rats: insights into inflammation and neurotrophic mechanisms
Human hair follicle stem cells improved memory and brain health in rats.
research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders
Psoriasis involves immune and genetic factors, and understanding these can improve treatments.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Hairy tale of signaling in hair follicle development and cycling
Hair growth and development are controlled by specific signaling pathways.
research Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo andIn Vitro
Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2
MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
research Alkylation of human hair keratin for tunable hydrogel erosion and drug delivery in tissue engineering applications
Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
research Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Myotonic Dystrophy—A Progeroid Disease?
Myotonic dystrophy may be classified as a segmental progeroid disorder.
research Membrane androgen receptors may mediate androgen reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Finasteride Enhances Stem Cell Signals of Human Dermal Papilla Cells
Finasteride boosts stem cell signals for hair growth.
research Advances in Stem Cell Therapy: Specific Applications in the Treatment of Cutaneous Radiation Syndrome
Stem cell therapy improves healing and reduces pain in cutaneous radiation syndrome.
research Cellular Senescence and Aging in Myotonic Dystrophy
Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth
Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
research Adipose-derived stem cells applied in skin diseases, wound healing and skin defects: a review
Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
research Water distribution in human hair microstructure elucidated by spin contrast variation small-angle neutron scattering
The technique showed that human hair has two main parts, with 68% being rigid and the rest flexible, and water swelling affects its structure.
research Clinical Snippets
Early sunburn treatment with certain inhibitors may reduce skin cancer risk.
research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
research Enzyme‐Instructed Self‐Assembly for Cellular Supramolecular Chemistry
EISA uses enzymes to create precise nanostructures in cells, offering new ways to design adaptive materials and therapies.
research Hair regeneration: Mechano-activation and related therapeutic approaches.
Mechanical stimulation and new therapies show promise for hair regrowth.
research Frontal Fibrosing Alopecia and the Role of Cosmeceuticals in Its Pathogenesis
Cosmeceuticals like sunscreens may trigger frontal fibrosing alopecia, but more research is needed.
research Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model
Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.
research Nitric oxide synergizes minoxidil delivered by transdermal hyaluronic acid liposomes for multimodal androgenetic-alopecia therapy
The new hair loss treatment combining nitric oxide and minoxidil in a special carrier is effective for hair regrowth.
research The Endocrine Function of the Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
research Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia
The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.