1 citations
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January 1995 in “Journal of Investigative Dermatology” RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
Androgen receptor overexpression can increase prostate cancer cell growth even without hormones.
48 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.
5 citations
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September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease” Hairless protein helps control hair growth by regulating vitamin D receptor activity.
4 citations
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June 2017 in “Anais Brasileiros De Dermatologia” Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.
April 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The vitamin D receptor helps control hair growth and may protect against certain skin tumors.
19 citations
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May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.
147 citations
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October 2004 in “Experimental dermatology” Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
August 2013 in “Nature Reviews Drug Discovery” New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
51 citations
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January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
4 citations
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February 2008 in “Cell stem cell” NFATc1 is crucial for keeping hair follicle stem cells inactive.
February 2024 in “PloS one” Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
February 2022 in “Research Square (Research Square)” Certain nutraceuticals may enhance hair growth without affecting the cancer-fighting properties of tamoxifen.
January 2016 in “UNESP Institutional Repository (São Paulo State University)” Melasma results from changes in the skin's pigment and structure, not just pigment cell growth.
August 2013 in “Nature Reviews Drug Discovery” New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.
5 citations
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July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.
10 citations
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August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
20 citations
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January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
42 citations
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December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
January 2017 in “Journal of Antivirals & Antiretrovirals” Treatment strategies for breast cancer affect blood health, causing issues like anemia and require nutritional counseling.
55 citations
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May 1985 in “Archives of Dermatology” Calcitriol-resistant rickets is an inherited disorder that affects hair growth and causes hair loss.
48 citations
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July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
3 citations
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August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The DNN-DTIs method accurately predicts drug-target interactions and is useful for drug repositioning.
January 2018 in “Computational Toxicology” Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.
March 2025 in “Laboratory Investigation” MESTSV is a rare tumor that is mostly benign but needs long-term monitoring due to potential recurrence.
16 citations
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January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Hair loss is caused by mechanical, thermal, and metabolic factors, not just hormones.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Hair loss is caused by mechanical, thermal, and metabolic stress, not just hormones.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Spironolactone effectively treats female pattern hair loss but requires ongoing use to maintain results.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Spironolactone effectively treats female pattern hair loss but requires ongoing use to maintain results.