research Nuclear Topology, Epigenetics, and Keratinocyte Differentiation
Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
Search
for
Sort by
Research
30 / 1000+ results 
research Topological Distribution of Wound Stiffness Modulates Wound-Induced Hair Follicle Neogenesis
The stiffness of a wound affects hair growth during healing, with less stiff areas growing more hair.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
research DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation
The HR protein's role as a repressor is essential for controlling hair growth.
research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Methods for Treating Androgenic Alopecia by Restoration of Morphogenetic Field Connectivity in Hair Follicle Networks
Restoring communication in hair follicle networks may treat hair loss and improve sexual dysfunction.
research Novel Tissue Mechanics-Guided Cellular Flows Enable the Evolution of Feather Follicles
Cellular flows and tissue mechanics guide feather follicle formation in birds.
research Post-Exposure Syndromes as State-Space Trapping: A set-theoretic perspective on PSSD and the post-exposure family.
Post-exposure syndromes are persistent conditions caused by past exposures, needing unique interventions.
research Post-Exposure Syndromes as State-Space Trapping: A set-theoretic perspective on PSSD and the post-exposure family.
Post-Exposure Syndromes are persistent conditions caused by past exposures, needing unique interventions.
research Integrated edge information and pathway topology for drug-disease associations
iEdgePathDDA effectively finds new drug-disease links, outperforming other methods.
research A Quantitative Measurement Method for Nuclear-Pleomorphism Scoring in Breast Cancer
A new method accurately measures cell changes in breast cancer.
research Skin regional specification and higher-order HoxC regulation
A specific DNA duplication in Polish chickens affects feather shape by altering gene expression.
research Novel tissue mechanics-guided cellular flows drive the formation of feather follicles
Feather follicles form through specific cellular flows and mechanical changes in the skin.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research Proliferation, but Not Apoptosis, Is Associated with Distinct β-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas
Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
research YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate
YAP and TAZ proteins control skin cell growth and repair.
research Methods for Treating Androgenic Alopecia by Restoration of Morphogenetic Field Connectivity in Hair Follicle Networks
Restoring hair follicle communication may treat hair loss and improve sexual dysfunction.
research Methods for Treating Disorders of Tissue Function by Restoration of Morphogenetic Field Connectivity: General Prior Art Disclosure
Restoring cell communication can treat tissue disorders.
research Methods for Treating Disorders of Tissue Function by Restoration of Morphogenetic Field Connectivity: General Prior Art Disclosure
Restoring cell communication can treat tissue disorders.
research Hutchinson-Gilford Progeria Syndrome—Current Status and Prospects for Gene Therapy Treatment
Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
research QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities
Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
research A Multi-Donor Ex Vivo Platelet Activation and Growth Factor Release Study Using Electric Pulses With Durations Up to 100 Microseconds
Electric pulses can effectively activate platelets and release growth factors, offering a better alternative to traditional methods.
research PKC downregulation upon rapamycin treatment attenuates mitochondrial disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Pharmacology of anabolic steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Hierarchical patterning modes orchestrate hair follicle morphogenesis
Hair follicle patterns form through a mix of self-organization and signaling interactions.
research Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Roles of steroid sulfatase in brain and other tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.