research Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes
BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
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research Development and evaluation of antisense shRNA-encoding plasmid loaded solid lipid nanoparticles against 5-α reductase activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Medications
Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss
Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.
research Lab Quality Management and Methodology
Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
research Gene therapy to enhance angiogenesis in chronic wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Bioengineering skin using mechanisms of regeneration and repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research Tissue homeostasis
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research The novel mechanisms and applications of exosomes in dermatology and cutaneous medical aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research Dormancy in the stem cell niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Edible seeds from Cucurbitaceae family as potential functional foods: Immense promises, few concerns
Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research The influence of interferon on healthy and diseased skin
Type I interferons play a key role in the development of various skin diseases.
research A Simple Method to Extract DNA from Hair Shafts Using Enzymatic Laundry Powder
DNA can be quickly and effectively extracted from hair using laundry powder.
research Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss
Fat-derived stem cells may help treat skin aging and hair loss.
research Patent Reports
New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
research Epigenetic regulation in adult stem cells and cancers
Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
research Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
research The blastema and epimorphic regeneration in mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
research High prevalence of chronic thyroiditis in patients with polycystic ovary syndrome
People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.
research Recent advances in oxasteroids chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research ENDOXAN ALOPECIA
Endoxan often causes hair loss, which usually starts in the third week of treatment.
research The transdermal inhibition of melanogenesis by a cell-membrane-permeable peptide delivery system based on poly-arginine
A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research Association of Gly972Arg variant of insulin receptor subtrate-1 and Gly1057Asp variant of insulin receptor subtrate-2 with polycystic ovary syndrome in the Chinese population
The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.
research Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice
Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.