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Experimental Assessment of 3-Meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-Alpha-Reductase Inhibitors in Silico and in Vivo Models

research Experimental Assessment of 3-meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors in silico and in vivo Models

January 2023 in “Bioorganičeskaâ himiâ”

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase

research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase

89 citations , February 1993 in “Journal of Medicinal Chemistry”

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

research An evaluation of the RapidHIT™ ID system for hair roots stained with Diamond™ Nucleic Acid Dye

December 2023 in “Forensic science international. Genetics”

The RapidHIT ID system can effectively get DNA profiles from hair roots with enough cells.

research Silver nanoparticles in medicine and technology: Synthesis, functionality and future prospects

3 citations , October 2024 in “World Journal of Advanced Research and Reviews”

Silver nanoparticles are useful in medicine and technology for their antibacterial properties and potential in drug delivery and dentistry.

research Changing the shape of hair with keratin peptides

47 citations , January 2017 in “RSC Advances”

Keratin peptides can change hair shape gently without harsh chemicals.

research Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work

70 citations , August 2019 in “European Journal of Medicinal Chemistry”

research ChemInform Abstract: Rα‐Reductase Inhibitors‐ — The Finasteride Story

November 2011 in “ChemInform”

Identification of Trichophyton Rubrum by Nested PCR Analysis from Paraffin Embedded Specimen in Trichophytia Profunda Acuta of the Glabrous Skin

research Identification of Trichophyton rubrum by Nested PCR Analysis from Paraffin Embedded Specimen in Trichophytia Profunda Acuta of the Glabrous Skin

23 citations , January 2005 in “Nihon Ishinkin Gakkai zasshi”

Nested PCR can reliably identify fungal infections when traditional methods fail.

research PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands

7 citations , January 2025 in “Journal of Experimental & Clinical Cancer Research”

PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.

Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands

research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands

November 2021 in “Pharmaceutical Sciences”

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

research Targeted radionuclide therapy for head and neck squamous cell carcinoma: a review

3 citations , August 2024 in “Frontiers in Oncology”

Targeted radionuclide therapy shows promise for improving head and neck cancer treatment but needs more research.

research 원저 : 모반세포 모반과 악성흑색종의 감별진단에 있어서 Peanut Agglutinin의 의의

January 1990 in “대한피부과학회지”

Peanut agglutinin staining helps differentiate malignant melanoma from nevocellular nevus.

Targeting Anti-Inflammatory Immunonanocarriers to Human and Murine Neutrophils via Ly6 Antigen for Psoriasiform Dermatitis Alleviation

research 1113 Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils via Ly6 antigen for psoriasiform dermatitis alleviation

April 2023 in “Journal of Investigative Dermatology”

The study created special nanoparticles that effectively deliver an anti-inflammatory drug to treat skin inflammation in psoriasis.

research A Convenient Synthesis of (16S,20S)-3β-Hydroxy-5α-pregnane-20,16-carbolactam and Its N-alkyl Derivatives

2 citations , May 2020 in “Molecules”

A new, efficient method was developed to synthesize a specific compound and its derivatives.

research The Influence of Electrode Potentials on the Extent of Reduction of Cystine in Hair Fibers by Reducing Agents

4 citations , April 1955 in “Textile Research Journal”

The effectiveness of reducing agents on hair fibers depends on their electrode potentials.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research Synthesis of avicequinone c and analogs toward the study of 5α-reductase inhibitory activity

January 2015

2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.

research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands#

16 citations , November 2018 in “Medicinal Chemistry”

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

research MG53 Mitigates Nitrogen Mustard-Induced Skin Injury

3 citations , July 2023 in “Cells”

MG53 helps reduce skin damage caused by nitrogen mustard.

Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways

research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways

24 citations , September 2005 in “Journal of Cellular Biochemistry”

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

5 citations , January 2018

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

research Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle

59 citations , January 2015 in “Nanoscale”

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

research Cardiac biopsy in myocarditis

2 citations , October 1990 in “The Lancet”

Some people have a genetic variation that makes them less effective at breaking down drugs.

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