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Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Researchers made new compounds that could potentially be developed into anticancer drugs.

The method produces finasteride with a 92% yield.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

These chemicals can be toxic, causing health issues like cancer, liver damage, and irritation.

Extracellular nucleic acids help start inflammation needed for tissue repair, but must be properly regulated.

The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Newly designed proteins can effectively degrade specific proteins in cells, offering a promising alternative for targeted protein degradation.

Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

Hexahydrobenzo[f]quinolines are effective at blocking the enzyme 5α-reductase.

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.

The enzyme from Bacillus cereus can be used in detergents and leather processing.

Chemotherapy toxicity might be reduced by using DNA neutralizing agents.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

The study found ways to create important compounds for male health from olive waste.

Minoxidil detects nitrite in water, creating a simple, cheap test.

A new compound effectively inhibits human 5α-reductase 1.

1,2,3,4-tetrahydroquinoline compounds are great for stable, pure blue hair dye.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

These chemicals can be toxic and cause health issues like irritation, liver damage, and cancer.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

Analog 23 is a promising compound for prostate cancer treatment.