research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1
Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
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research Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium
FoxN1 gene is essential for proper thymus structure and preventing hair loss.
![Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)](/images/research/d743d32f-3115-48ff-9697-2f2d56130701/small/14175.jpg)
research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)
The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
research Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation
A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
research Clobetasol/minoxidil
research The Epochal Transition Vol.1 No.8 (March 2026) 时代跃迁 第八期
The "Danti Original Source" method can reverse androgenetic alopecia.
research First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases
Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
research Conversion of C57Bl/6 mice from a tumor promotion–resistant to a –sensitive phenotype by enhanced ornithine decarboxylase expression
Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21
research Androgens
research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Tcf3 and Lef1 are key in deciding skin stem cell roles.
research Miscellaneous Exosome Trials
research Mutations in Sterol O-Acyltransferase 1 (Soat1) Result in Hair Interior Defects in AKR/J Mice
A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.
research OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases
OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
research Foxn1 in Skin Development, Homeostasis and Wound Healing
Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
research Thrombospondin-1 Plays a Critical Role in the Induction of Hair Follicle Involution and Vascular Regression During the Catagen Phase
Thrombospondin-1 is crucial for hair follicle regression and reduced blood vessel growth during the catagen phase.
research 881 Ionizing radiation triggers dedifferentiation of outer root sheath cells into stem cell-like progenitors for hair follicle regeneration
research Molecular and Functional Characterization of Clonogenic Human Thymic Epithelial Cells
Human thymus has stem cells that can self-renew and maintain their identity.
research A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice.
CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
research Nutraceuticals as anti-angiogenic agents: hopes and reality.
Some plant-based compounds might help control the growth of new blood vessels if further research confirms their effectiveness.
research Cicatricial alopecia secondary to radiation therapy: case report and review of the literature.
Keeping radiation doses under 16 Gy may reduce permanent hair loss.
research High-dose steroid pulse therapy for the treatment of severe alopecia areata.
High-dose steroid pulse therapy effectively regrows hair in severe multifocal alopecia areata.
research [Implication of VEGF, steroid hormones and neuropeptides in hair follicle cell responses].
Hair growth is regulated by a combination of hormones, blood vessels, and nerve signals.
research Ferret adrenal-associated endocrinopathy.
Surgery successfully treated the ferret's adrenal issue, leading to hair regrowth and improved health.
research Transcriptional regulation analysis and the potential transcription regulator site in the extended KAP6.1 promoter in sheep
research Pancytopenia in epidemic dropsy: a case report
Contaminated mustard oil caused severe health issues, including pancytopenia, in a family.
research Unusual presentation with polymenorrhagia and markedly high 17-hydroxy progesterone levels in a lady with Non-Classic Congenital Adrenal Hyperplasia.
A woman with non-classic CAH had unusual heavy periods and high hormone levels, improved with treatment.
research A systematic review of procedural modalities in the treatment of lichen planopilaris, frontal fibrosing alopecia, and discoid lupus erythematosus
research Determining the Quality of Life of People with Alopecia areata and Associated Factors in Tertiary Hospitals in Capital City of Malaysia
Unmarried individuals and those with diabetes have a poorer quality of life with alopecia areata.
research Hair Growth Stimulation in Testosterone-Induced Alopecic Mice: A Comparative Study between Topical Clove Oil 10% Topical Minoxidil 5% <u>Research Article</u>Journal of the Faculty of Medicine BaghdadPrint ISSN: 0041-9419, Online ISSN: 2410-8057DOI: https://doi.org/10.32007/jfacmedbaghdad2977. Hair Growth Stimulation in Testosterone-Induced Alopecic Mice: A Comparative Study between Topical Clove oil 10% Topical Minoxidil 5%
Clove oil may help hair growth like minoxidil, but more human tests are needed.