TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
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November 2010 in “Journal of molecular medicine” FoxN1 gene is essential for proper thymus structure and preventing hair loss.
Frontal hair in male pattern baldness shows reduced growth and thickness.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.
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August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Sex hormones and antiandrogens can either stimulate or inhibit human hair follicle cell growth depending on the dose.
March 2012 in “Journal of The American Academy of Dermatology” Temporal triangular alopecia usually starts in early childhood and treatment with Minoxidil has limited effectiveness.
Mutations in keratin genes may link hair disorders to dental decay.
January 2024 in “Revista del Centro Dermatológico Pascua” Avoiding damage and using specific shampoo and supplements improved the hair condition.
June 2021 in “International journal of research in dermatology” Shaving and avoiding brushing improved the patient's beard hair condition.
56 citations
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July 2001 in “International Journal of Clinical Pharmacology and Therapeutics” People obsessed with looking young may need therapy to address deeper issues.
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June 2013 in “Journal of Dermatological Case Reports” Olmsted syndrome is a rare skin disorder causing thickened skin and other symptoms.
OCT can effectively diagnose different stages of hair loss non-invasively.
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
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June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
December 1991 in “Annals of the New York Academy of Sciences” 38 citations
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April 2005 in “Journal of Investigative Dermatology” Human hair follicle cells can become fat and bone cells, useful for therapy.
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August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink, leading to skin issues, and blue light can help hair grow.
5 citations
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January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
1 citations
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August 2016 in “Journal of Investigative Dermatology” Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.
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December 1982 in “Developmental Medicine & Child Neurology” Hair-shaft abnormalities can indicate neurological disorders, some of which are treatable.
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January 2023 in “Development” Hox genes are crucial for development and tissue maintenance, affecting structures and functions throughout life.
199 citations
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January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
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December 2003 in “Gene” The ovine Hoxc-13 gene is crucial for hair formation and may have other skin functions.
26 citations
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March 1981 in “Clinical Endocrinology” Oestrogen does not affect adrenal androgen levels in children and adolescents.
June 2014 in “The Journal of Dermatology” A patient with a rare chromosome condition also had a rare type of hair loss.
January 2004 in “Chinese Journal of Dermatology” Injecting specific oligonucleotides can change hair growth and structure by altering a gene.