research Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
The method effectively measures drug impact on DHT levels in prostate treatments.
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720-750 / 1000+ resultsresearch Efficacy of dutasteride on androgenetic alopecia recalcitrant to finasteride
research Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Management of Clinical Side Effects of DMPA
To improve use of the contraceptive DMPA among adolescents, effectively manage side effects like menstrual changes and weight gain through counseling and guidance.
research 5α‐Reductase Inhibitors
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Computational Evaluation of Dibenzo Compounds as Potential Dual Inhibitors of Androgen Receptor and 5α-Reductase
Some dibenzo compounds might help treat cancer with fewer side effects.
research Adverse events with finasteride or dutasteride: FAERS
Lower finasteride doses had more side effects; dutasteride caused back pain; more research needed on post-finasteride syndrome.
research Finasteride
research Determination of Oxymatrine in Human Plasma by HPLC-MS
A method was created to measure oxymatrine in human blood.
research Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin
The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
research P6590Androgenic effects on ventricular repolarization: a translational study from pharmacovigilance databases to iPSC-cardiomyocytes
Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
research A pharmacovigilance study of drug‐reduced male semen quality based on the Food and Drug Administration adverse event reporting system database
Some drugs can reduce male semen quality.
research Signal Detection of Depression and Suicidality Associated with Finasteride and Dutasteride: Updated Pharmacovigilance Evidence and Recommendations for Comprehensive Psychiatric Assessment
Finasteride may cause depression and suicidal thoughts, especially in young men.
research The effect of Finasteride in Tourette Syndrome: results of clinical trial
research Finasteride 1 mg in alopecia: sexual dysfunction, suicidal ideation. Providing balanced information to male patients is key.
research Tamoxifen for flutamide/finasteride-induced gynecomastia
Tamoxifen effectively treats gynecomastia without causing impotence.
research New drugs: Iobenguane sulfate
Lifestyle changes are more effective than metformin in reducing type 2 diabetes risk in women with PCOS.
research Finasteride 5 mg/day treatment of patterned hair loss in normo-androgenetic postmenopausal women
Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.
research New Aromatic Esters of Progesterone as Antiandrogens
New progesterone-based compounds can block male hormones.
research PROSPECTIVE EVALUATION ON SEXUAL DYSFUNCTION PERSISTENCE, WORSENING OR IMPROVEMENT IN BPH PATIENTS AFTER FINASTERIDE OR DUTASTERIDE TREATMENT
Finasteride and dutasteride can affect sexual function in BPH patients.
research Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients
Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.
research Risk of age-related macular degeneration in men receiving 5α-reductase inhibitors: a population-based cohort study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
research RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF FINASTERIDE AND TAMSULOSIN IN TABLET FORMULATIONS
A reliable method was developed to measure Tamsulosin and Finasteride in tablets accurately.
research The effectiveness of finasteride and dutasteride used for 3 years in women with androgenetic alopecia
Finasteride and dutasteride effectively stop or reverse hair loss in women with androgenetic alopecia, with dutasteride being more effective for women under 50.
research Polyherbal chocolate supplementation - a novel adjuvant therapy for polycystic ovary syndrome (PCOS)
Polyherbal chocolate may help manage PCOS symptoms.
research Long-term safety and efficacy of dutasteride in the treatment of male patients with androgenetic alopecia
Dutasteride safely promotes hair growth and reduces hair loss, with mild side effects.
research Minoxidil (Mx) as a prophylaxis of doxorubicin – induced alopecia
Minoxidil not effective in preventing chemotherapy-induced hair loss.
research Transdermal delivery of finasteride invasomes using taguchi robust design method
Invasomes with 0.5% limonene greatly improve skin delivery of finasteride.
research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6‐Hz and Kindling Models of Epilepsy
Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.