January 2026 in “Dermatology Practical & Conceptual” Nail changes are common in alopecia areata and can indicate its severity.
The nail immune system is similar to hair but different from skin, with fewer immune markers.
September 2023 in “Cureus” Nails can reveal important health information about skin and body conditions.
4 citations
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January 1981 in “PubMed” Hair medullary cells in mammals vary in complexity, with humans having more structured cells similar to inner root sheath cells.
4 citations
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April 2019 in “JAAD Case Reports” DPR can cause skin, hair, and nail issues, sometimes appearing later in life.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
18 citations
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November 2005 in “European Journal of Cell Biology” Keratin gene clusters in humans and marsupials are similarly organized.
March 2025 in “International Journal of Clinical Dermatology” Psychodermatosis is reclassified based on brain-skin interaction, dividing conditions into psychogenic and psychosomatic categories.
July 2024 in “Journal of Investigative Dermatology” Hair follicles are crucial for maintaining skin barrier function.
2 citations
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May 2024 in “International Journal of Dermatology”
17 citations
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September 2010 in “Pediatric dermatology” A 15-year-old with KID syndrome developed a rare skin condition called PEHFN.
26 citations
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December 2015 in “International Journal of Dermatology” Trichodynia is a painful scalp condition linked to hair loss and inflammation, often with anxiety, affecting more women and needing better treatment options.
23 citations
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April 2003 in “Journal of Structural Biology” Keratin structure changes during keratinization, but the exact model remains uncertain.
103 citations
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December 1986 in “Journal of Investigative Dermatology” March 1990 in “Journal of Dermatological Science” 95 citations
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January 2009 in “Journal of Biomedical Optics” Nanoparticles penetrate hair follicles better when their size matches the cuticula thickness.
August 2018 in “Pediatric Dermatology” A baby had a unique skin condition with a pale patch and surrounding dark hairs, not linked to other health issues.
60 citations
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December 2003 in “Journal of Investigative Dermatology” K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.
396 citations
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May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
April 2017 in “Journal of Dermatological Science” Asymmetric hair follicle differentiation causes the unique shape of kinky hair.
1 citations
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October 2019 in “International journal of contemporary pediatrics” A 12-year-old boy with twenty nail dystrophy, a condition affecting all nails, was treated conservatively due to its self-limiting nature and good prognosis.
1 citations
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February 2025 in “Scientific Reports” The method effectively analyzes skin tissue changes, especially in the arrector pili muscle and nerve fibers with hair follicles.
April 2012 in “Journal of the American Academy of Dermatology” Dermoscopy can help diagnose tinea capitis in children by looking for comma hairs, black dots, and broken hairs with white bands.
221 citations
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June 1999 in “In Vitro Cellular & Developmental Biology - Animal” 110 citations
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January 1983 in “Brain Research Reviews” Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
January 2006 in “Chinese Journal of Dermatology” Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
39 citations
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June 2012 in “Journal of Structural Biology” Disulfide bonds are crucial for hair structure during keratinization.
January 2005 in “Chinese Journal of Veterinary” Hairless mice lose hair by 3-4 weeks, develop thicker, folded skin, and show pigmentation differences.
4 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.
March 2026 in “Indian Journal of Dermatopathology and Diagnostic Dermatology” Corkscrew hairs can help diagnose trichotillomania.