28 citations
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March 2014 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” The document concludes that hair curvature can be explained by the growth patterns caused by the shape and separation of cells in the hair follicle and is affected by specific molecular pathways.
October 2024 in “Developmental Dynamics” The document highlights recent advances in developmental biology, focusing on three studies. The first study establishes a zebrafish model for Diamond-Blackfan anemia like (DBAL), showing that epoa-deficient zebrafish can be used to screen treatments for anemia, with recombinant human EPO improving erythrocyte numbers. The second study investigates the role of Alx4 in craniofacial and hair development, using Alx4fx/fx conditional mice to explore the mechanisms of ALX4-related disorders and alopecia, finding that Alx4 loss leads to developmental defects and hair loss. The third study examines the mTORC1 signaling pathway's role in retinal development, demonstrating that its disruption in retinal progenitor cells causes lamination deficits and visual behavior loss, highlighting mTORC1's importance in CNS histogenesis.
1 citations
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January 2018 in “ScholarWorks (Central Washington University)” Stress and PCOS together may increase depression and anxiety-like behaviors.
118 citations
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January 2004 in “European Journal of Cell Biology” Balanced protease activity is crucial for healthy skin and hair development.
25 citations
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September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
30 citations
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June 2016 in “Journal of Human Genetics” Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.
1 citations
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May 2018 in “Psychology, Health & Medicine” The two-factor model fits better for Chinese patients' understanding of illness causes than the original four-factor model.
23 citations
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March 2023 in “eLife” Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
47 citations
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February 2014 in “Journal of Cutaneous Pathology” Matrical tumors share a common growth mechanism involving the Wnt pathway and consistent PHLDA1 expression.
1 citations
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December 2022 in “Sultan Qaboos University medical journal” The machine learning model accurately predicts Systemic Lupus Erythematosus in Omani patients.
133 citations
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July 1994 in “Journal of Dermatological Science” Human hair growth can be influenced by certain growth factors and has specific metabolic needs.
30 citations
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December 1996 in “Journal of Investigative Dermatology” 1 citations
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October 2019 in “International Journal of Dermatology and Venereology” Zebrafish help understand genetic causes of skin pigment disorders like albinism.
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
44 citations
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June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
April 2018 in “Journal of Investigative Dermatology” The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
January 2026 in “Frontiers in Medicine” A child has a rare hair and skin disorder due to specific gene variants, suggesting broader genetic testing is needed.
6 citations
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January 2015 in “Indian Dermatology Online Journal” PEODDN is a rare skin disorder with limited treatment options, best treated with laser therapy.
13 citations
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January 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
September 2025 in “International Journal of Medical Informatics” A machine learning model can predict scarring in lichen planopilaris using factors like vitamin D levels and diagnostic delay.
Recognizing mild or atypical cases of ectodermal dysplasia is crucial for better treatment and future planning.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Stem cell niche exit in C. elegans is influenced by Sh1 cell membrane protrusions.
January 2007 in “Durham e-Theses (Durham University)” Hair growth and shedding involve specific cell changes and gene roles.
November 2023 in “Biomolecules” The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
June 1996 in “Journal of Dermatological Science” April 2023 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
188 citations
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June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
A skin model using hair and skin cells can mimic human skin for research.
December 2025 in “ILDS-DEV” 1 citations
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August 2012 in “Research in Pharmaceutical Sciences”