research Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft
Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.
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research Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue
Caspase-7 has functions in skin and hair that are not related to cell death.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
research Hair growth-promoting effect of recombinant human sonic hedgehog proteins
Sonic hedgehog proteins may help grow hair.
research Region-specific reversal of epidermal planar polarity in the rosette fancy mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
research The role of Wnt and Shh signaling systems in noggin-induced tumorigenesis
Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.
research Abstract 152
TLR3 activation helps improve skin and hair follicle healing in mice.
research In This Issue
Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata
Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
research The balance of Bmp6 and Wnt10b regulates the telogen-anagen transition of hair follicles
BMP6 and Wnt10b control whether hair follicles are resting or growing.
research Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia
IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
research Role of stem/progenitor cells in reparative disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Genetic Fate Mapping Using Site-Specific Recombinases
The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
research Dickkopf-related Protein 2 Promotes Hair Growth by Upregulating the Wnt/β-catenin Signaling Pathway in Human Dermal Papilla Cells
Dickkopf-related Protein 2 can help hair grow by activating a specific cell pathway.
research The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research A Preview of Selected Articles
New treatments for hair loss, fertility, and wound healing are being explored.
research Diffuser Haarausfall und klinische Endokrinologie: Neue Erkenntnisse
Hormones significantly affect hair growth and loss, with potential for new treatments.
research Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells
Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
research Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits
Ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes and influencing hair follicle phases.
research The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits
Ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes and influencing hair follicle phases.
research Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia
Researchers discovered how to control Claudin expression in cells, aiding cancer and regenerative medicine research.
research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy
Stem cells are more dynamic and adaptable than previously believed.
research Lgr5 marks cycling, yet long-lived, hair follicle stem cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
Human skin can make serotonin and melatonin, which help protect and maintain it.