September 2024 in “International Journal of Molecular Sciences” Hydrangea serrata extract may promote hair growth and improve hair health.
April 2023 in “Journal of Investigative Dermatology” Taking nicotinic acid supplements might help with acne by affecting the skin's oil glands, but high doses are needed.
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
November 2022 in “Journal of Investigative Dermatology” DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
Rat liver stem cells can grow into organoids and help treat liver diseases.
27 citations
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February 2020 in “EMBO Reports” MEX3A is crucial for maintaining intestinal stem cells in mice.
9 citations
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October 2022 in “Nature Communications” The DiLiCre mouse model is an effective tool for precise genome editing using light.
2 citations
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October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” RANKL helps regenerate lung cells, potentially aiding lung repair in diseases like COPD.
July 2017 in “Cancer Research” Krt15+ cells in mice can resist radiation, regenerate tissue, and start tumors, suggesting new cancer treatment targets.
291 citations
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April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
125 citations
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March 2017 in “Micromachines” Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
64 citations
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August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
47 citations
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June 2013 in “Biology of blood and marrow transplantation” Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
42 citations
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January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
21 citations
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August 2024 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
15 citations
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May 2023 in “npj Regenerative Medicine” Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
13 citations
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July 2024 in “Circulation Research” The epicardium is vital for heart repair and regeneration, offering potential for new heart disease therapies.
9 citations
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September 2022 in “Journal of Clinical Investigation” Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
9 citations
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December 2020 in “International Journal of Medical Sciences” iPSCs help understand and treat neurodevelopmental disorders.
4 citations
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August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The tool iCOUNT helps understand how stem cells divide and affect tissue development and repair.
2 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Androgen signaling reduces Wnt activity, affecting prostate stem cell growth.
The method effectively creates uniform, viable cell spheroids for 3D cell culture.
December 2025 in “Nature Communications” Blocking IL-17a can improve age-related smell loss in mice.
July 2025 in “PNAS Nexus” A new tool accurately identifies human cornea cell states and key factors.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
September 2022 in “Research Square (Research Square)” Macrophages help maintain mammary stem cells and balance through specific signaling.
October 2018 in “Current Opinion in Genetics & Development” The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
July 2024 in “Journal of Investigative Dermatology” JW0061 may be a new treatment for hair loss by promoting hair growth through WNT signaling.
182 citations
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November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.