research Artificial Pigmented Human Skin Created by Muse Cells
Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
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research LB1671 Large-scale skin scRNA-seq profiling highlights distinct body site-specific ligand-receptor interactions and pathways in keratinocytes
Different body areas have unique skin cell communication patterns, explaining why certain skin diseases occur in specific regions.
research Localization of Type I Human Skin Collagenase in Developing Embryonic and Fetal Skin
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Large-scale cultivation of transplantable dermal papilla cellular aggregates using microfabricated PDMS arrays
Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
research Tissue-Engineered Skin Preserving the Potential of Epithelial Cells to Differentiate into Hair After Grafting
Tissue-engineered skin can support hair growth after grafting, especially with mouse-derived dermis.
research Skin‐on‐a‐chip strategies for human hair follicle regeneration
New technologies show promise for better hair regeneration and treatments.
research In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing
A new skin treatment using a patient's own cells healed chronic wounds effectively and was preferred over traditional grafts.
research Neonatal murine skin-derived cells transplanted using a mini-chamber model produce robust and normal hair
Transplanted baby mouse skin cells grew normal hair using a new, efficient method.
research A novel immune competent murine hypertrophic scar contracture model: A tool to elucidate disease mechanism and develop new therapies
The model helps understand scar contraction and develop new treatments.
research Multiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research Culture of the human pilosebaceous unit, hair follicle and sebaceous gland
The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
research Organoids and organ chips in ophthalmology
Organoids and organ chips can improve eye disease research and treatment.
research Characterization of Hair Follicle Development in Engineered Skin Substitutes
Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
research Feature identification of skin diseases and laser therapy with a portable optical coherence imaging system
A portable imaging system shows promise for diagnosing skin diseases and checking laser treatment effects.
research Biomedical applications of organoids in genetic diseases
Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
research Hair-bearing human skin generated entirely from pluripotent stem cells
Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
research Merkel cell polyomavirus infection and persistence modelled in skin organoids
Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
research Reprogramming of human keratinocytes into functional cardiomyocytes
Human skin cells can be turned into heart cells.
research Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures
Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies
3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
research Animal and in vitro Models for the Study of Hair Follicles
Understanding hair follicles through various models can help develop new treatments for hair disorders.
research Fabrication and characterization of epithelial scaffolds for hair follicle regeneration
Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
research Abstract 5020: Characterization of epidermal stem cells in SKH1 hairless mice, a widely used mouse model to investigate ultraviolet radiation carcinogenesis.
SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
research Microvascular Remodeling Strategy for Skin Rejuvenation through Microenvironmental Reprogramming and Appendage Restoration
research Advances and applications of biomimetic biomaterials for endogenous skin regeneration
Biomimetic biomaterials can improve skin healing by mimicking natural tissue and reducing immune rejection.
research Morphological characteristics and notes of the skin in preclinical toxicity assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages
Proteolytic activity in mouse skin changes with hair cycle stages, peaking in early anagen.
research Comparison of Activities Dependent on Glutathione S-Transferase and Cytochrome P-450 IA1 in Cultured Keratinocytes and Reconstructed Epidermal Models
Reconstructed skin models are useful for studying how skin processes certain chemicals.
research Matrix-free cryo-microneedles array patch for 3D hair follicle organoids delivery` and rapid hair regeneration
The new cryo-MAP technique enables rapid and successful hair growth by transplanting hair follicle organoids.