11 citations
,
April 2020 in “Journal of Dermatological Treatment” Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.
4 citations
,
October 2022 in “Nutrients” Personalized diets, like the Mediterranean Diet and low carb diets, can help manage PCOS symptoms in obese women, and probiotics may enhance weight loss and improve metabolic health. More research is needed to find the best diet strategies.
1 citations
,
March 2017 in “European Journal of Cancer Prevention”
January 2026 in “RSC Advances” Epristeride's metabolism in zebrafish helps improve doping detection methods.
April 2006 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Oral finasteride, combined with drospirenone, improved hair loss in 62% of premenopausal women, with no reported side effects.
1 citations
,
April 2013 in “PubMed”
10 citations
,
October 2010 in “International Journal of Andrology” Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
48 citations
,
July 2023 in “Pediatric Dermatology” The ALLEGRO phase 2b/3 trial evaluated the efficacy and safety of ritlecitinib, a JAK3/TEC family kinase inhibitor, in 105 adolescents aged 12-17 with alopecia areata and ≥50% scalp hair loss. Over 48 weeks, 25%-50% of patients in the ritlecitinib groups achieved significant hair regrowth (SALT score ≤20), compared to 0% in the placebo group. Additionally, 44%-80% of adolescents reported moderate to great improvement in their condition with ritlecitinib, versus 10%-22% with placebo. Common adverse events included headache, acne, and nasopharyngitis, but no severe adverse events were reported. Overall, ritlecitinib showed promising efficacy and a favorable safety profile for treating alopecia areata in adolescents.
2 citations
,
September 2024 in “Journal of the American Academy of Dermatology” Deuruxolitinib significantly helps regrow scalp hair in adults with moderate to severe alopecia areata.
32 citations
,
July 2001 in “Endocrine Practice” Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
32 citations
,
October 2003 Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
May 2023 in “Arteriosclerosis, thrombosis, and vascular biology” Finasteride may slow down heart disease by lowering cholesterol and reducing inflammation.
May 2025 in “Scientific Reports” Oxyresveratrol promotes hair growth and may help treat hair loss.
6 citations
,
April 2016 in “Journal of the Formosan Medical Association” Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
January 1994 in “Toxicological Sciences” Lower dosages of 2-(difluoromethyl)-dl-ornithine might reduce side effects, supporting further research.
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
15 citations
,
January 2024 in “The AAPS Journal” 50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.
December 2023 in “Biointerface Research in Applied Chemistry” Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
Dutasteride may become the top choice for treating hair loss.
A new lipid-based formula using myristyl myristate can improve estradiol treatment for hair loss.
14 citations
,
January 2015 in “ABCD” The surgery effectively promoted and maintained weight loss in obese women during the first year.
December 2003 in “British Journal of Urology” 17 citations
,
March 1992 in “PubMed” 24 citations
,
January 2017 in “International Journal of Trichology”
A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.
192 citations
,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
7 citations
,
August 2023 in “EClinicalMedicine” Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
January 2018 in “Surgical and Cosmetic Dermatology” Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.
3 citations
,
December 2016 in “Universal journal of pharmaceutical research” Finasteride, a drug used for anti-hyperplasia, can be effectively delivered in the form of matrix tablets.