July 2023 in “Stem Cells Translational Medicine” Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
June 2008 in “Wound Repair and Regeneration” Msx-2 gene removal speeds up skin wound healing in mice.
63 citations
,
March 2018 in “Experimental Dermatology” Collagen XVII is vital for skin structure, hair stem cell support, and skin cell regulation.
101 citations
,
July 2021 in “Nature Communications” 4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” EX104 effectively promotes hair growth and regenerates follicles in androgenetic alopecia.
42 citations
,
July 2010 in “European Journal of Cell Biology” Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.
65 citations
,
May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
83 citations
,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
41 citations
,
March 2016 in “The Journal of Clinical Endocrinology & Metabolism” In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
36 citations
,
October 2023 in “Periodontology 2000” L-PRF is effective for bone regeneration in the mouth.
65 citations
,
August 2013 in “Acta Biomaterialia” The new matrix improves skin regeneration and graft performance.
October 2025 in “Journal of the Endocrine Society” Ovarian hyperthecosis can cause high testosterone and symptoms like hair loss, and surgery can help improve these symptoms.
7 citations
,
January 1973 in “Calcified Tissue International” Hair follicle tissue can induce mineral formation, likely due to a potent nucleator.
August 2025 in “Acta Biomaterialia” The new hydrogel speeds up wound healing by reducing inflammation and promoting tissue growth.
294 citations
,
January 2016 in “Stem Cells International” Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
April 2019 in “Journal of Investigative Dermatology” Skin grafts from related donors significantly healed chronic wounds in patients with a severe skin condition over a year.
5 citations
,
July 1988 in “Facial Plastic Surgery” Tissue expansion is a useful method for reconstructive surgery with good results and room for further enhancement.
January 2026 in “Ciencia Latina Revista Científica Multidisciplinar” Exosome-based therapy successfully restored hair in a 14-year-old with difficult-to-treat alopecia areata.
11 citations
,
January 2013 in “Veterinary dermatology” Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.
5 citations
,
January 2016 in “Elsevier eBooks” Using a specific binding agent and low doses of FK506 can stimulate stem cells, speeding up skin healing by 25% and improving skin quality in rats and mice.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Androgens increase growth factors in skin cells, which may lead to acne.
October 2022 in “Regenerative Biomaterials” A special gel with stem cells can create new hair follicles.
67 citations
,
December 2009 in “International Journal of Dermatology” Hormonal changes in skin may cause stretch marks.
September 2017 in “Journal of Investigative Dermatology” BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
1 citations
,
November 2008 in “Acta crystallographica” Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.
1 citations
,
February 2024 in “Journal of Microscopy and Ultrastructure” Exosomes from stem cells speed up wound healing.
154 citations
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October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” Estrogen affects hair growth and skin cell multiplication.
September 2025 in “Scientific periodicals of Ukraine” Early diagnosis and treatment stopped hair loss and improved the condition.
207 citations
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.