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Did you mean Hair Epithelial Cells?

GlossaryHair Epithelial Cells

specialized cells forming the outer layer of hair follicles

Hair epithelial cells are specialized cells that make up the outer layer of the hair follicle, which is the structure in the skin that produces hair. These cells play a crucial role in the growth and regeneration of hair by dividing and differentiating to form the various parts of the hair shaft and the surrounding follicle.

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Nestin as a Marker of Unipotent Epithelial Progenitor Cell Differentiation into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles

research Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles

May 2022 in “Research Square (Research Square)”

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

research VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro

35 citations , October 2013 in “Journal of Dermatological Science”

VEGF165 influences hair follicle cell growth and movement through VEGFR-2 activation.

Nestin as a Marker of Unipotent Epithelial Progenitor Cells Differentiating into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles

research Nestin as a marker of unipotent epithelial progenitor cells differentiate into outer root sheath keratinocytes in embryonic and adult hair follicles

June 2022 in “Research Square (Research Square)”

Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

research Anagen hair follicle repair: Timely regenerative attempts from plastic extra‐bulge epithelial cells

18 citations , January 2019 in “Experimental Dermatology”

Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.

research A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells

2 citations , January 1989

Researchers developed a method to grow skin-like tissue from hair cells.

research Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells

31 citations , December 1991 in “Annals of the New York Academy of Sciences”

ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.

research Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle

107 citations , May 1999 in “Archives of Dermatological Research”

Basal cell carcinoma may start from parts of tiny hair follicles.

research Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX2 and SOX9 in the human hair follicle

33 citations , March 2015 in “Experimental Dermatology”

LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.

research Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle

46 citations , November 1998 in “Experimental Cell Research”

K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.

ERK1/2 Pathway Involvement in Enhancement of Fatty Acids from Phaeodactylum Tricornutum Extract on Hair Follicle Cell Proliferation

research ERK1/2 Pathway Is Involved in the Enhancement of Fatty Acids from Phaeodactylum tricornutum Extract (PTE) on Hair Follicle Cell Proliferation

2 citations , January 2020 in “BioMed Research International”

Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.

research Organotypic Cocultures as Models to Study Cell-Cell and Cell-Matrix Interactions of Human Hair Follicle Cells

18 citations , January 1994 in “Skin Pharmacology and Physiology”

Human dermal fibroblasts and hair papilla cells help outer root sheath cells grow and develop properly.

research Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles

87 citations , February 2000 in “Journal of Investigative Dermatology”

Stem cells in developing hair follicles move to specific areas as they mature.

Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque¹

33 citations , January 1997 in “Endocrinology”

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

research [Hair follicle cell mixture forms hair follicle-like structures after subcutaneous implantation in nude mice].

September 2007 in “PubMed”

Implanted human scalp cells can regenerate hair-like structures in mice.

research The location and proliferation of human hair follicle stem cells

January 2006 in “Chinese Journal of Dermatology”

Mesenchymal cells are essential for hair follicle stem cell growth.

research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles

248 citations , April 1988 in “Differentiation”

Human and bovine hair follicles have distinct cytokeratins specific to hair-forming cells.

research Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.

4 citations , February 2013 in “PubMed”

A3 antibody helps identify key cells in rat hair follicle development.

research Pilomatricoma can differentiate not only towards hair matrix and hair cortex, but also follicular infundibulum, outer root sheath and hair bulge

18 citations , March 2009 in “Experimental Dermatology”

Pilomatricoma can develop into various hair-related structures.

Treatment With Cyclohexyl Salicylate, an Olfactory Receptor 2A4/7 Agonist, Promotes Human Hair Follicle Growth and Bulge Stem Cell Progeny Expansion

research 732 Treatment with cyclohexyl salicylate, an olfactory receptor 2A4/7 agonist, promotes human hair follicle growth and bulge stem cell progeny expansion

July 2022 in “Journal of Investigative Dermatology”

Cyclohexyl salicylate promotes human hair growth and increases certain hair follicle stem cell progeny.

research Fabrication and characterization of epithelial scaffolds for hair follicle regeneration

4 citations , May 2012 in “Tissue Engineering and Regenerative Medicine”

Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.

research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein

51 citations , February 2004 in “Journal of Investigative Dermatology”

MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.

research The chemotactic effect of a dermal papilla cell-derived factor on outer root sheath cells

47 citations , April 2001 in “Journal of Dermatological Science”

IGF-I and HGF attract and stimulate hair follicle cells to move.

research Sex Hormones and Antiandro Growth of Dermal Papilla H ens Influence In Vitro Ce Is and Outer Root Sheath Keratinocytes of Human Hair Follicles

January 1993

Testosterone and dihydrotestosterone can slow down the growth of certain hair follicle cells.

research Hair follicle regeneration from human pluripotent stem cells

January 2017 in “Journal of clinical & experimental dermatology research”

Scientists have found a way to create hair follicles from human stem cells, which could potentially be used to treat hair loss.

research Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells

173 citations , July 1995 in “Biochemical and biophysical research communications”

Male hormones promote hair cell growth by using a growth factor from nearby skin cells.

research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes

12 citations , July 2019 in “Veterinary Dermatology”

Nestin-expressing progenitor cells become outer root sheath keratinocytes.

research Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo andIn Vitro

140 citations , December 1998 in “Journal of Investigative Dermatology”

Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.

research Original Article : Fabrication and Characterization of Epithelial Scaffolds for Hair Follicle Regeneration

January 2012 in “조직공학과 재생의학”

The study found that certain three-dimensional scaffolds can help regenerate hair effectively.

research Epithelial–mesenchymal transition in keloid tissues and TGF‐β1–induced hair follicle outer root sheath keratinocytes

46 citations , July 2015 in “Wound repair and regeneration”

Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.

research Co‐culture of Human Hair Follicles and Dermal Papillae in a Collagen Matrix

36 citations , November 1990 in “The Journal of Dermatology”

Dermal papillae enhance hair follicle growth and structure.