September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
15 citations
,
July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
Natural α-hydroxyl acids cause skin exfoliation by activating TRPV3 channels.
8 citations
,
July 2004 in “Journal of morphology” Marsupial hair structure and keratin distribution are similar to placental mammals.
10 citations
,
August 2018 in “Experimental Dermatology” Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.
1 citations
,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
January 2007 in “Chinese journal of plastic surgery” Sodium fluoride increases cell death in hair follicles, but sodium selenite can reduce this effect.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” QLT0267 stops hair follicle cell growth and movement.
29 citations
,
February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
April 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
44 citations
,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
28 citations
,
November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
23 citations
,
July 1994 in “Journal of Dermatological Science” Pili torti hair twists due to uneven outer root sheath cell development.
96 citations
,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
58 citations
,
March 1985 in “Journal of The American Academy of Dermatology” The document concludes that electrolysis and thermolysis can permanently remove hair but calls for better regulation to ensure safety, and notes a possibility of hair regrowth and rare complications.
26 citations
,
December 2022 in “Journal of the American Academy of Dermatology” Monkeypox skin lesions show full-thickness skin death and swollen skin cells, with the virus found in affected cells.
15 citations
,
September 2012 in “PTR. Phytotherapy research/Phytotherapy research” Ginsenosides Rb₁ and Rd may help prevent hair loss by promoting hair cell growth.
4 citations
,
November 2018 in “Journal of comparative pathology” The three adipokines—leptin, adiponectin, and resistin—are present in various cells of normal dog skin.
3 citations
,
January 1989 in “The Nishinihon Journal of Dermatology” A hair cyst can become cancerous, showing specific keratins from the hair sheath.
128 citations
,
February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
104 citations
,
July 1994 in “The Journal of Cell Biology” Basonuclin helps keratinocytes multiply and prevents them from fully maturing.
94 citations
,
October 1994 in “The Journal of Cell Biology” Too much keratin 16 in mice skin causes abnormal skin thickening and structure.
25 citations
,
September 1995 in “Biochemistry and Cell Biology” High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
November 2025 in “Biomedicines” Targeting pyroptosis may offer new treatments for alopecia areata, but more research is needed.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
Suppressing ODC activity reduces tumor growth in hair follicles.
15 citations
,
August 2017 in “International Journal of Molecular Medicine” Panax ginseng extract may help prevent hair loss caused by DKK-1.
September 2017 in “Journal of Investigative Dermatology” Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
59 citations
,
October 2017 in “Proceedings of the National Academy of Sciences” ZIP10 is crucial for skin development and maintaining healthy skin.
38 citations
,
November 1991 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Keratins 8 and 14 can help identify and diagnose benign skin tumors.