research Ovarian sex steroid receptors and sex hormones in androgenized rats
High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
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930-960 / 1000+ resultsresearch END OF LIFE CARE IN INPATIENT PSYCHIATRY: A CASE STUDY ON END-STAGE ALZHEIMER'S DISEASE
The case shows the need for psychiatrists to manage end-of-life care for dementia patients, including respecting patients' wishes and using hospice services.
research Finasteride
Finasteride can cause multiple side effects like tremors, dry skin, and rapid aging.
research LB891 Analysis of breast health outcomes in women on oral 5-alpha reductase inhibitors: A single-center retrospective cohort study
5-alpha reductase inhibitors don't increase breast cancer or benign breast disorder risk in women.
research Association of DNA damage with vitamin D and hair heavy metals of obese women
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
research Androgenic alopecia; the risk–benefit ratio of Finasteride
Patients should discuss risks with doctors before using finasteride for hair loss.
research Used Right, IV Arsenic Is Safe & Effective
Intravenous arsenic is safe and effective for treating certain blood cancers.
research Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss-Side Effect
Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
research Can You Really Have Too Much of a Good Thing?: How Benevolent Tax Policies Have Attributed to the Explosion of Health Care Costs and How New Policies Threaten to Do More of the Same
research Cardiometabolic risks in polycystic ovary syndrome: long-term population-based follow-up study
Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.
research Sexual adverse events-related to dutasteride e finasteride: analysis of real-life data from Eudra-Vigilance database
research Expanding the therapeutic potential of neuro(active)steroids: a promising strategy for hyperdopaminergic behavioral phenotypes
Neurosteroids may help treat disorders with too much dopamine activity.
research Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options
Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.
research Supplementary Material for: Finasteride and Suicide: A Postmarketing Case Series
The study explored a possible link between finasteride use and suicide.
research Azathioprine‐induced severe myelosuppression accompanied by massive hair loss and painful oral ulcer in an autoimmune hepatitis patient with NUDT15 minor variant: A case report
Genetic testing is crucial before giving azathioprine to avoid severe side effects.
research Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia
Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.
research Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research News in brief
Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.
research Association of Frailty Index with Clinical BPH Progression and Serious Adverse Events: the MTOPS Trial
Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.
research Retrospective analysis of the risk of hyperkalaemia in women older than 65 years of age prescribed spironolactone for female-pattern hair loss
research Drug repurposing: Clinical practices and regulatory pathways
Drug repurposing offers faster, cheaper drug development but faces challenges like safety, ethics, and funding.
research Safety and use of oral minoxidil in pediatric patients: a systematic review and meta-analysis
Oral minoxidil may help with pediatric hair disorders but has notable side effects.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Contraception hormonale et cancer du sein : Une question de contexte
Birth control pills slightly increase the risk of breast cancer, especially if used before the first full-term pregnancy.
research A Retrospective Study on the Safety of Systemic Minoxidil for Hair Loss in the Older Population
Systemic minoxidil is generally safe for older adults, but caution is needed for those with heart risks.
research Spironolactone
Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
research Evaluation of risk of SSRI-associated impotence and low libido in men exposed to finasteride
Finasteride and SSRIs together increase impotence and low libido risk in men.
research The Influence of the MDR1 C3435T Polymorphism on Methotrexate Responsiveness in Rheumatoid Arthritis Patients
The MDR1 C3435T polymorphism does not significantly affect methotrexate response in rheumatoid arthritis patients.
research 33813 Retrospective study of the prevalence of hyperkalemia in women taking spironolactone for acne, hair loss, and hirsutism
Dermatologists should monitor potassium levels in women taking spironolactone for acne, hair loss, and hirsutism.
research Characteristics of Hypertrichosis Induced by 24-week Low-dose (5 mg Daily) Oral Minoxidil in Male Pattern Hair Loss Treatment
Low-dose oral minoxidil often causes excess hair growth but doesn't significantly affect quality of life.