September 2022 in “F1000Research” Removing hair from mice without reproductive glands led to grey hair, possibly helping to understand greying in aging.
15 citations
,
August 2014 in “Journal of dermatological science” Pueraria thunbergiana extract may help prevent hair from turning gray.
The herbal mixture Xiantene may help treat common baldness, and men who grey early tend to be less bald but more grey.
17 citations
,
January 2018 in “International Journal of Trichology” Low levels of iron, copper, and calcium may contribute to premature hair graying.
62 citations
,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
October 2021 in “QJM: An International Journal of Medicine” Low iron levels are linked to premature graying of hair, but vitamin D levels are not.
1 citations
,
May 2023 in “AYUSHDHARA” Ayurveda suggests holistic methods to address premature greying of hair.
August 2012 in “Fertility and Sterility” Premature gray hair may indicate reduced ovarian reserve but doesn't lower pregnancy chances.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
Good nutrition may help prevent premature hair graying.
June 2025 in “Clinical and Experimental Dermatology” A 76-year-old man's grey hair turned back to its original color after radiotherapy.
January 2012 in “한국미용학회지” Graying hair is caused by changes in gene expression affecting cell functions.
7 citations
,
June 2020 in “Experimental dermatology” Researchers found that certain lipids, especially vitamin D3, are lower in prematurely grey hair than in pigmented hair.
7 citations
,
January 2018 in “PubMed” Low levels of iron, copper, and calcium may cause early hair graying.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” Gray hair requires special coloring techniques and care to maintain quality and strength.
April 2026 in “npj Regenerative Medicine” Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
December 2025 in “Journal of Ayurveda and Integrated Medical Sciences” Modern lifestyle factors like stress and pollution cause premature greying of hair.
August 2024 in “Applied Sciences” Plant extracts may help prevent or reverse hair graying.
January 2004 in “Giornale di Metafisica: revista bimestrale di filosofia” Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
September 1941 in “The Science News-Letter” 2 citations
,
November 2024 in “JAAD reviews.” Certain drugs can change hair color, either lightening or darkening it.
1 citations
,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
December 2015 in “European Journal of Pediatric Dermatology” Newborns can experience temporary hair loss in bands, unrelated to sleeping position.
19 citations
,
July 2009 in “Clinical and Experimental Dermatology” The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.
12 citations
,
November 2004 in “Photochemistry and Photobiology” Superoxide dismutase (SOD) can prevent hair graying in mice.
2 citations
,
January 1997 in “Mapping” Gambogic Amide may prevent hair greying and promote hair growth by maintaining hair pigmentation.
September 2018 in “CRC Press eBooks” Hair and nail disorders can cause changes in scalp pigmentation, especially with sun exposure and alopecia.
7 citations
,
March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
36 citations
,
November 2016 in “European journal of dermatology/EJD. European journal of dermatology” Some medications can cause rare hair color changes, and reporting these side effects is important for patient quality of life.