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research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

82 citations , July 2012 in “Brain pathology”

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

The Involvement of ROS on Androgen Inducible TGF Beta 1 Regulation Derived from Dermal Papilla Cells: A Suggestive Implication of ROS on Androgenetic Alopecia

research The involvement of ROS on androgen inducible TGF beta 1 regulation derived from dermal papilla cells; a suggestive implication of ROS on androgenetic alopecia

January 2008 in “Journal of The American Academy of Dermatology”

ROS may affect hair loss related to hormones.

research Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice

October 2014 in “Cancer research”

Blocking mTORC1 reduces skin tumor growth in mice.

research Coregulation of Genetic Programs by the Transcription Factors NFIB and STAT5

20 citations , March 2014 in “Molecular Endocrinology”

NFIB and STAT5 work together to control specific genetic programs in cells.

research TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition

82 citations , February 2017 in “Cold Spring Harbor Perspectives in Biology”

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

research Regulatory T cells in skin utilize the Cxcr4-Cxcl12 axis to promote hair follicle regeneration

October 2025 in “Cell Reports”

Regulatory T cells help hair growth by using the Cxcr4-Cxcl12 pathway.

research Integrating multi-omics analyses of Nonomuraea dietziae to reveal the role of soybean oil in [(4′-OH)MeLeu]4-CsA overproduction

1 citations , July 2017 in “Microbial Cell Factories”

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

research DKK3–CKAP4 signaling drives fibroimmune remodeling and hair follicle miniaturization in androgenetic alopecia

May 2026 in “Theranostics”

research 575 INTASYL self-delivering RNAi: A flexible platform to treat dermatological malignancies

July 2024 in “Journal of Investigative Dermatology”

INTASYL is a promising, adaptable RNAi technology for treating skin cancers.

Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision Between Stem Cell Maintenance and Differentiation

research Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation

1 citations , December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.

research KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway

18 citations , July 2023 in “International Journal of Molecular Sciences”

KY19382 speeds up wound healing by activating a specific cell signaling pathway.

SOX2 in the Skin: Roles in Biology and Pathology

research SOX2 in the Skin

1 citations , September 2015 in “Elsevier eBooks”

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

research HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression

132 citations , February 2002 in “Journal of Biological Chemistry”

HOXC13 is crucial for regulating hair keratin genes in hair follicles.

research Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis

June 2023 in “Journal of biological chemistry/The Journal of biological chemistry”

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

research Reversal of alopecia areata, osteoporosis follow treatment with activation of Tgr5 in mice

14 citations , July 2021 in “Bioscience Reports”

Activating Tgr5 may help treat hair loss and bone loss.

research Abstract 12: LGR6+ Epithelial Stem Cell Augmentation of Fracture Healing

April 2018 in “Plastic & Reconstructive Surgery Global Open”

LGR6+ stem cells may improve bone healing.

research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

24 citations , July 2017 in “Structure”

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

research 780 Novel mechanism of UVB-mediated pigmentation through the axis of ATP-P2X7

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

research Wnt/β‐catenin and ERK pathway activation: A possible mechanism of photobiomodulation therapy with light‐emitting diodes that regulate the proliferation of human outer root sheath cells

43 citations , September 2017 in “Lasers in Surgery and Medicine”

LED light therapy may help hair growth by activating certain cell pathways.

research Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis

1 citations , July 2025 in “JCI Insight”

Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.

research Single-Cell Transcriptomics to Map Cellular Heterogeneity in Tissue Regeneration Models

December 2025 in “Drug Discovery and Molecular Docking (DDMD)”

Single-cell transcriptomics reveals detailed cellular diversity and key pathways in tissue regeneration.

research A symphony of signals: the intricate role of lncRNAs in dermatological disorders

1 citations , November 2025 in “Clinical and Experimental Medicine”

lncRNAs are important for understanding and treating skin diseases.

research Hairless down-regulates expression of Msx2 and its related target genes in hair follicles

14 citations , April 2013 in “Journal of dermatological science”

Hairless protein reduces Msx2 gene activity, affecting hair follicle development.

research Treatment of androgenetic alopecia by exosomes secreted from hair papilla cells and the intervention effect of LTF

August 2023 in “Journal of Cosmetic Dermatology”

Exosomes from hair papilla cells and the Chinese medicine Liao Tuo Fang can potentially promote hair growth and could be used to develop hair growth drugs.