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960-990 / 1000+ resultsresearch [G-proteins, receptor signal transduction, and growth hormone secretion].
The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.
research Application of big data analytics in minoxidil drug development: a data-driven model for predicting efficacy and side effect risks
The model predicts minoxidil's effectiveness and side effects better than traditional methods.
research METABOLISM AND ACTION OF ANDROGEN IN THE SKIN
Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.
research The Case of the Elusive Androgen
The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
research The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta?
Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
research Treatment of hirsutism with the pure antiandrogen flutamide
Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
research Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride
The research helps understand how finasteride works and aids drug development.
![Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions](/images/research/2aedba8c-b0ac-4fa3-9ac7-9f375a016bba/small/15581.jpg)
research Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions
Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
research An improved synthesis of finasteride from 4-androsten-3,17-dione
The new method makes finasteride cheaper and easier to produce.
research Immunohistochemistry study of pentoxifylline in the treatment of alopecia induced by cyclophosphamide in male rats
Pentoxifylline helps hair regrowth in rats with hair loss.
research Production of biologically active oxidized derivatives of finasteride through metabolism byAspergillus nigerculture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
research Recovery effects of active oxygen scavengers on murine hair follicle-derived keratinocyte proliferation suppressed by androgen
Active oxygen scavengers can reverse the suppression of hair cell growth caused by androgens.
research Atroposelective Synthesis of Biaryl N‐Oxides via Cu‐Catalyzed De Novo Heteroaromatic N‐Oxide Ring Formation
A new method efficiently creates biaryl N-oxides with potential for cancer treatment and drug development.
research Differential cardiometabolic outcomes of leuprolide versus spironolactone in women with polycystic ovary syndrome
Leuprolide may better manage cholesterol and blood pressure in PCOS than spironolactone.
research PLASMA UNBOUND AND UNCONJUGATED ANDROGENS IN ORIENTAL MEN
Oriental men may have lower androgen activity affecting hair growth despite similar testosterone levels to Caucasian men.
research Beyond Boundaries: The Transformative Potential of Spironolactone in Female Pattern Hair Loss
Spironolactone effectively treats female pattern hair loss but requires ongoing use to maintain results.
research Inhibition of 5α-reductase alters pregnane metabolism in the late pregnant mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research Hair growth and androgen responses in hirsute women treated with continuous cyproterone acetate and cyclical ethinyl oestradiol
The treatment significantly reduced hair growth and male hormone levels in hirsute women.
research First case of V281+I172N/V281L CYP21A2 genotype associated with congenital adrenal hyperplasia form. A case report from South Italy
New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.
research BH04 Growing interest: a survey of low-dose oral minoxidil prescribing for hair loss
Low-dose oral minoxidil is increasingly used by dermatologists in the UK and Ireland to treat various hair loss conditions.
research Intermolecular NH 2 -/Carboxyl-terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity
Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.
research Modern approach to the treatment of patients with androgen-dependent dermatopathies
Cyproterone acetate improves skin symptoms and quality of life in women with androgen-related issues.
research VIRILISING OVARIAN TUMOUR
In post-menopausal women, signs of increased male hormones should be checked for possible ovarian cancer.
research COVID‐19, androgens, and androgenic alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
research Potential adverse effects of long-term testosterone therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Testosterone replacement in 49,XXXXY syndrome: andrological, metabolic and neurological aspects
Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
research FINASTERIDE AND PSA
research Synthesis, Biological Evaluation and in silico Studies of Novel 5α-aza-Bhomo-3,5-secosteroids as Potential 5-reductase Inhibitors
research Can oral minoxidil be the game changer in androgenetic alopecia? A comprehensive review and meta-analysis comparing topical and oral minoxidil for treating androgenetic alopecia
Oral minoxidil is an effective alternative for hair loss but may cause more unwanted hair growth.