18 citations
,
September 2021 in “Journal of Neuroendocrinology” Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
April 2019 in “Journal of the Endocrine Society” Glucocorticoid treatment lowered androgen levels but didn't improve hirsutism or ovulation and caused weight gain.
9 citations
,
December 1977 in “Archives of Dermatology” Systemic steroids can effectively treat alopecia areata with manageable side effects.
January 2017 in “STARS (University of Central Florida)” Steroid hormones can be preserved in ancient hair, revealing insights into past health and fertility.
January 2026 in “GSC Biological and Pharmaceutical Sciences” Adapalene, Diosmin, and Azelastine could be repurposed to treat onchocerciasis.
4 citations
,
October 2024 in “Heliyon” CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.
2 citations
,
December 2001 in “Dermatologic Therapy” Steroids may not work well for alopecia areata because of high unoccupied receptors and low thioredoxin levels.
March 2025 in “Journal of Endocrinology and Metabolism” Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
8 citations
,
May 1996 in “Endocrinology” Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
12 citations
,
December 2009 in “Neuroscience” GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
October 2025 in “F1000Research” Postmenopausal women with excess male hormones may have ovarian tumors, and surgery usually cures them.
January 2025 in “Haematology International Journal” These ovarian conditions cause high testosterone levels.
7 citations
,
February 2025 in “Stem Cell Research & Therapy” Human hair follicle stem cells improve ovarian function in mice with damaged ovaries.
1 citations
,
September 2024 in “Journal of Clinical & Translational Endocrinology” PCOS women have more severe metabolic issues and higher androgen levels than hyperandrogenic women without PCOS.
April 2023 in “Research Square (Research Square)” A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.
11 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” October 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Rodent models of PCOS show some similar and some different lipid changes compared to humans.
8 citations
,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
164 citations
,
January 2003 in “Drugs”
6 citations
,
April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New progesterone-based compounds can block male hormones.
14 citations
,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Adapalene, Diosmin, and Azelastine may effectively treat onchocerciasis.
1 citations
,
March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Adapalene, Diosmin, and Azelastine may effectively treat onchocerciasis.
December 2025 in “Scientific Reports” Gut microbiota and metabolic pathways may play a key role in PCOS development.
The document's conclusion cannot be provided because the document is not available or cannot be read.
1 citations
,
February 2015 in “Revista Acadêmica Ciência Animal” A mare had a functional ovary with a tumor containing cartilage and bone.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
65 citations
,
April 2007 in “Chemistry and Physics of Lipids” Steroid hormones change the size, charge, and stability of DPPC liposomes.
101 citations
,
November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.