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research The crosstalk between PTEN ‐induced kinase 1‐mediated mitophagy and the inflammasome in the pathogenesis of alopecia areata

6 citations , June 2023 in “Experimental Dermatology”

Targeting mitophagy may help treat alopecia areata by reducing inflammasome activation.

research Homozygous missense mutation in theLIPHgene causing autosomal recessive hypotrichosis simplex in a Chinese patient

2 citations , December 2013 in “Journal of dermatology”

A specific gene mutation causes a rare hair loss condition in a Chinese patient.

research The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End ofKRT10

22 citations , September 2014 in “JAMA dermatology”

Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.

research A New Clinical Variant of Hereditary Localized Alopecia: Report of a Chinese Family Mapped to Chromosome 2p25.1–2p23.2

2 citations , March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new type of hereditary hair loss in a Chinese family is linked to chromosome 2p25.1–2p23.2.

Perspectives on MicroRNAs Targeting DKK1 for Developing Hair Regeneration Therapy

research Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy

12 citations , October 2021 in “Cells”

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

research Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice

1 citations , December 2020 in “International journal of molecular sciences”

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

research A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies

2 citations , August 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

A specific mutation in the K25 gene causes a rare genetic disorder with curly hair at birth and later hair loss, along with dental issues.

research Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development

10 citations , May 2020 in “Frontiers in cell and developmental biology”

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

Hunting the Hair Cycle Clock: Evidence That Mitochondrially Localized MPZL3 Is a Key Element in Murine and Human Hair Follicles

research 715 Hunting the hair cycle clock (HCC): Evidence that mitochondrially localized MPZL3 is a key HCC element in murine and human hair follicles

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

MPZL3 is important for controlling the hair growth cycle in mice and humans.

research ISID1394 - Long non-coding RNA AL136131.3 inhibits hair growth through mediating glycolysis in androgenetic alopecia

May 2023

The RNA AL136131.3 slows down hair growth and speeds up hair loss by affecting sugar breakdown in hair follicles.

research MiR-325-3p functions as a suppressor miRNA and inhibits the proliferation and metastasis of glioma through targeting FOXM1

16 citations , December 2021 in “Journal of Integrative Neuroscience”

miR-325-3p can slow down brain tumor growth by targeting FOXM1.

research Commentary on BRCA1-Associated Protein-1 Tumor Predisposition Syndrome in a Patient With Numerous Basal Cell Carcinomas

January 2019 in “Dermatologic Surgery”

research Injury suppresses Ras cell competitive advantage through enhanced wild-type cell proliferation

1 citations , January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Injury boosts normal skin cell growth, reducing cancer cell advantage.

research 266 Myristoylphorbol Acetate (MPA) Enhances Metastasis Via Up-regulation of Eph A2 Transcription Activity

July 2012 in “European journal of cancer”

MPA increases cancer spread by boosting Eph A2 activity.

research ELL Facilitates RNA Polymerase II–Mediated Transcription of Human Epidermal Proliferation Genes

4 citations , May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

ELL is crucial for gene transcription related to skin cell growth.

research Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene

27 citations , November 1991 in “Journal of Investigative Dermatology”

research Arabidopsis ZINC FINGER PROTEIN1 Acts Downstream of GL2 to Repress Root Hair Initiation and Elongation by Directly Suppressing bHLH Genes

101 citations , November 2019 in “The Plant Cell”

AtZP1 protein stops root hair growth in plants by blocking certain genes.

research Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine

24 citations , October 2019 in “Genes”

A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.

research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology

June 2019 in “International journal of dermatology and venereology”

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

research Tyrosine kinase inhibition and grey hair

59 citations , March 2003 in “The Lancet”

Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.

research Immunohistochemical analysis of procathepsin L and cathepsin B in cutaneous Kaposi's sarcoma

6 citations , February 1997 in “International Journal of Dermatology”

Kaposi's sarcoma lesions might originate from benign tissue changes.

research Phospholipase C‐δ1 is an essential molecule downstream of Foxnl, the gene responsible for the nude mutation, in normal hair development

54 citations , October 2007 in “The FASEB Journal”

Phospholipase C-δ1 is crucial for normal hair development.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

research 811 Mitochondrial MPZL3 in the inner root sheath regulates human hair follicle cycling ex vivo

1 citations , July 2024 in “Journal of Investigative Dermatology”

MPZL3 protein affects hair growth cycles and could help manage hair loss.

research Exosomal miR ‐199a‐3p From Dermal Papilla Cells Regulates Hair Follicle Pigmentation by Targeting POU2F1 in Melanocytes

April 2026 in “The FASEB Journal”

This study investigates the role of exosomal miR-199a-3p from dermal papilla cells (DPCs) in regulating hair follicle pigmentation by targeting POU2F1 in melanocytes. The research demonstrates that DPC-derived exosomes (DPC-Exos) are internalized by melanocytes, enhancing their proliferation, reducing apoptosis, and increasing melanin production. miR-199a-3p was identified as a key exosomal cargo, directly targeting POU2F1, a gene involved in melanogenesis. The study also shows that exosomal miR-199a-3p promotes hair follicle growth and regulates melanogenesis-related genes. These findings highlight a DPC-MC regulatory axis mediated by miR-199a-3p/POU2F1, offering potential therapeutic targets for pigmentation disorders and strategies for animal coat color modulation.

research Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration

8 citations , August 2023 in “Journal of Investigative Dermatology”