Search

for
Search:

Sort by

Research

270-300 / 1000+ results

The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain

70 citations , December 2004 in “Differentiation”

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

research Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis

26 citations , September 2001 in “Journal of Investigative Dermatology”

BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.

research Keratin 15 promotes a progenitor cell state in basal keratinocytes of skin epidermis

December 2025 in “The Journal of Cell Biology”

Keratin 15 helps maintain skin cell growth and repair.

research Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

136 citations , March 1998 in “Oncogene”

Overexpression of E2F1 can lead to skin tumors and disrupt hair growth.

research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection

4 citations , May 2025 in “npj Parkinson s Disease”

PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.

research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology

33 citations , February 2012 in “British Journal of Dermatology”

Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.

CRABP1 Enhances Proliferation of Dermal Papilla Cells in Hu Sheep via Wnt/β-Catenin Pathway

research CRABP1 Enhances the Proliferation of the Dermal Papilla Cells of Hu Sheep through the Wnt/β-catenin Pathway

September 2024 in “Genes”

CRABP1 boosts hair cell growth in Hu sheep by affecting key genes.

research 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia

1 citations , November 2022 in “Journal of Investigative Dermatology”

ALRN-6924 may prevent hair loss caused by chemotherapy.

research An ultrahigh-sulphur keratin gene of the human hair cuticle is located at 11q13 and cross-hybridizes with sequences at 11p15

15 citations , January 1991 in “Mammalian Genome”

research Genetic Variants at 20p11 Confer Risk to Androgenetic Alopecia in the Chinese Han Population

9 citations , August 2013 in “PLOS ONE”

Genetic variants at 20p11 increase baldness risk in Chinese Han people.

research Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11

27 citations , April 2004 in “Biochemical and Biophysical Research Communications”

Two new gene clusters important for hair formation were found on human chromosome 11.

research Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11*1

1 citations , May 2004 in “Biochemical and Biophysical Research Communications”

Two new gene clusters important for hair formation were found on human chromosome 11.

research The association between rs2476601 polymorphism in PTPN22 gene and risk of alopecia areata

9 citations , May 2019 in “Medicine”

The C-allele and CC-genotype in the PTPN22 gene lower the risk of alopecia areata.

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

12 citations , June 2020 in “Frontiers in Cell and Developmental Biology”

The PP2A-B55α protein is essential for brain and skin development in embryos.

research Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2

175 citations , September 1998 in “British Journal of Dermatology”

Keratin 17 gene mutations cause both steatocystoma multiplex and pachyonychia congenita type 2.

research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development

14 citations , May 2016 in “International Journal of Molecular Sciences”

PP2Acα is essential for proper hair and skin development.

research Abstract 3372: Mouse keratinocyte side-population plays an important role during malignant progression to skin squamous cell carcinomas

3 citations , April 2012 in “Cancer research”

Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.

research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle

January 2007

research Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶

28 citations , January 2005 in “Photochemistry and Photobiology”

Protein kinase C epsilon may increase skin cancer risk by affecting nearby cells.

research HDAC1-Overexpressing Dermal Papilla Cell-Derived Extracellular Vesicles Modulate p53 and Wnt/β-Catenin Signaling to Rescue Hair Follicle Regeneration in Androgenetic Alopecia

January 2026 in “Biomaterials”

research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

6 citations , December 2019 in “Frontiers in genetics”

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits

42 citations , January 2017 in “Genes”

The gene KAP22-1 affects wool yield and fiber shape in sheep.

research Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation

2 citations , January 2014 in “Photochemical & photobiological sciences”

Grasp protein helps maintain skin health after UVB exposure.

research DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation

1 citations , May 2023 in “Biochemical and Biophysical Research Communications”

Blocking DKK1 with siRNA can improve hair growth.

research Long-read RNA sequencing reveals extensive transcript isoform changes in a patient with IFAP syndrome with a recurrent intronic MBTPS2 variant

April 2026 in “Human Genome Variation”

Long-read RNA sequencing can identify complex gene changes in IFAP syndrome.

research A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration

September 2016 in “Journal of Dermatological Science”

The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.

research A New Clinical Variant of Hereditary Localized Alopecia: Report of a Chinese Family Mapped to Chromosome 2p25.1–2p23.2

2 citations , March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new type of hereditary hair loss in a Chinese family is linked to chromosome 2p25.1–2p23.2.

research Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and its Relevance for the Pachyonychia Congenita Phenotype

88 citations , June 2000 in “Journal of Investigative Dermatology”

Keratin 17 is important for hair and nail structure and affects pachyonychia congenita symptoms.

research A Mutation in the Serum and Glucocorticoid-Inducible Kinase-Like Kinase (Sgkl) Gene is Associated with Defective Hair Growth in Mice

6 citations , January 2004 in “DNA Research”

A mutation in the Sgkl gene causes defective hair growth in mice.

research Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle

53 citations , August 2005 in “The Journal of Cell Biology”

Sgk3 is essential for normal hair follicle growth and maintenance.

← Previous page Next page →