Search

for
Search:

Glossaryp38 MAPK pathway

regulates cellular responses to stress and inflammation

The p38 MAPK pathway, also known as the p38 mitogen-activated protein kinase pathway, is a signaling pathway in cells that responds to stress stimuli, such as inflammation and UV radiation. It plays a crucial role in regulating cellular processes like inflammation, cell growth, and apoptosis (programmed cell death). This pathway is significant in various diseases, including cancer and autoimmune disorders, and is a target for therapeutic interventions.

Related Terms

Sort by

Research

30 / 993 results

research Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways

30 citations , December 2021 in “Frontiers in Microbiology”

Cepharanthine effectively reduces Herpes Simplex Virus Type 1 by blocking certain cell pathways and promoting cell death.

research Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway

April 2025 in “Drug Design Development and Therapy”

Jiawei Erzhiwan helps hair growth in androgenetic alopecia by affecting specific cell pathways.

research Sinapic Acid Promotes Browning of 3T3‐L1 Adipocytes via p38 MAPK/CREB Pathway

29 citations , January 2020 in “BioMed Research International”

Sinapic acid may help fight obesity and promote hair growth.

research Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways

9 citations , February 2025 in “Journal of Nanobiotechnology”

Biomimetic nanovesicles can speed up diabetic wound healing by regulating immune cell behavior and metabolism.

research Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways

March 2026 in “Molecules”

Camellia sinensis seed flavonoids can reduce skin inflammation and damage from UV rays.

Particulate Matter Induces Inflammatory Response in Human Outer Root Sheath Cells via Oxidative Stress-Dependent MAPK and JAK-STAT Signaling Pathways

research 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Particulate matter causes inflammation in hair cells, potentially harming hair growth.

research Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo

6 citations , May 2022 in “Aging”

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

research Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes

January 2014 in “edoc (University of Basel)”

Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.

research Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues

8 citations , December 2015 in “The Journal of Physiology”

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

research Abstract 2962: Chemotherapy induced senescence drives peripheral neuropathy

March 2024 in “Cancer Research”

Eliminating senescent cells can prevent and reverse chemotherapy-induced peripheral neuropathy.

research The potential application of natural products in cutaneous wound healing: A review of preclinical evidence

45 citations , July 2022 in “Frontiers in Pharmacology”

Natural products can help heal wounds by affecting key biological pathways.

Bisphenol-A Antagonizes the Rapidly Modulating Effect of Dihydrotestosterone on Spinogenesis and Long-Term Potentiation of Hippocampal Neurons

research Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons

10 citations , December 2017 in “Chemosphere”

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

research Microenvironment-Responsive Recombinant Collagen XVII-Based Composite Microneedles for the Treatment of Androgenetic Alopecia

May 2025 in “Acta Biomaterialia”

The new microneedle treatment effectively promotes hair growth better than minoxidil.

The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5-Independent Manner

research The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner

May 2025 in “Experimental Dermatology”

Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.

research Protective Effect of Iris germanica L. Rhizome-Derived Exosome against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes

October 2023 in “Applied sciences”

Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.

research Il-10 family members as novel responders to genotoxic stress

January 2015 in “ScholarlyCommons (University of Pennsylvania)”

IL-19 and IL-24 help cells respond to DNA damage and could be targeted for cancer and age-related disease treatments.

research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway

25 citations , September 2020 in “Molecules”

Quercitrin may help treat hair loss by promoting hair growth and improving cell health.

research Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways

14 citations , September 2018 in “International Journal of Molecular Sciences”

Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.

research Malva verticillataseed extracts upregulate the Wnt pathway in human dermal papilla cells

25 citations , August 2015 in “International Journal of Cosmetic Science”

Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.

research Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment

September 2024 in “Journal of Ethnopharmacology”

Terminalia bellirica extracts effectively promote hair regrowth and treat androgenetic alopecia.

research Network Pharmacology Reveals Curcuma aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia

July 2024 in “Biology”

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

In Vitro Hair Growth-Promoting Effects of Araliadiol via the p38/PPAR-γ Signaling Pathway in Human Hair Follicle Stem Cells and Dermal Papilla Cells

research In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells

December 2024 in “Frontiers in Pharmacology”

Araliadiol may promote hair growth like minoxidil without being toxic.

research LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway

53 citations , April 2016 in “Stem cell research & therapy”

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms

research The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms

21 citations , April 2018 in “Journal of Dermatological Science”

Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.

research Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling

8 citations , June 2022 in “Frontiers in bioengineering and biotechnology”

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

research Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy

32 citations , August 2019 in “Nature Communications”

Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.

Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer

research Epimedium brevicornum Maxim. Extract exhibits pigmentation by melanin biosynthesis and melanosome biogenesis/transfer

6 citations , September 2022 in “Frontiers in pharmacology”

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

research Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways

3 citations , September 2024 in “International Journal of Molecular Sciences”

Mathematical modeling helps understand and predict the MAPK cell signaling pathway.

research Combined Physicochemical and Transcriptomic Analyses Reveal the Effect of Black Wolfberry Ferment on Alopecia

May 2025 in “Journal of Food and Nutrition Research”

Black wolfberry ferment may help regrow hair in cases of androgenetic alopecia.

research Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling

September 2025 in “Frontiers in Medicine”

Angiopoietin-1 helps hair cells survive and grow, making it a potential treatment for hair loss.