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Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

BMP signaling is essential for the development of touch domes.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

p63 and p73 regulate the vitamin D receptor, affecting cancer cell behavior and vitamin D sensitivity.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

The PML protein helps prevent skin cancer in mice.

People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.

Too much keratin 16 in mice skin causes abnormal skin thickening and structure.

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

Grasp protein helps maintain skin health after UVB exposure.

Keratin 10 end domains may increase skin cancer risk by reducing cell death.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

Certain genes help dermal papillae cells in hair follicles grow and group together.

Inhibiting ACE2 improves skin regeneration during tissue expansion.

AgK114 protein helps in hamster skin injury recovery.

The role of certain genes in skin cell development may be linked to psoriasis, but the connection is unclear.

Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.

Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.

Phosphatidylinositol 4-kinases are crucial for root growth, defense, and immunity in Arabidopsis thaliana.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Human and mouse TGase3 enzymes are similar but differ near the activation site, crucial for their function in skin and hair development.

Brepocitinib reduces interferon signaling in hidradenitis suppurativa patients.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

ATP-sensitive potassium channels are important for hair growth.

p63 may influence skin cancer development and cell differentiation.