research Clinicopathologic and molecular characterization of a series of sporadic trichoblastic neoplasms
Sporadic trichoblastic neoplasms generally don't recur or spread, with one case showing a specific genetic fusion.
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research Fondation René Touraine
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research An Investigation of Keratin 15 Function by Small Interfering Ribonucleic Acid Technology
Keratin 15 affects cell behavior and characteristics in skin cells.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research New insights into the functions of Cox-2 in skin and esophageal malignancies
Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
research Primary cicatricial alopecia: Recent advances in understanding and management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
research Tailored chromatin modulation to promote tissue regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3
Deleting Snai2 and Snai3 causes fatal autoimmunity.
research MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway
Gsdma3 affects hair growth by controlling Wnt5a, which influences hair cell development.
research Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation
Hair growth genes work better with more glucose due to changes in gene-regulating markers.
research Immunological control of skin development: from homeostasis to developmental pathologies
Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research Melanocytes: The new Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
research Trichoblastic Carcinoma (“Malignant Trichoblastoma”) with Lymphatic and Hematogenous Metastases
Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.
research Wnt signaling in skin organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research Epigenetic control of skin and hair regeneration after wounding
Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Undariopsis peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways
Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.
research Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review)
The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
research Hair follicle regeneration suppresses Ras-driven oncogenic growth
Hair follicle regeneration may slow tumor growth.
research Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research The regulatory role of the tetrapeptide A cSDKP in skin and hair physiology and the prevention of ageing effects in these tissues – a potential cosmetic role
AcSDKP may help prevent skin and hair aging and promote their growth.
research An efficient, non-invasive approach for in-vivo sampling of hair follicles: design and applications in monitoring DNA damage and aging
A new painless method to collect hair follicles helps study DNA damage and aging.
research Hair follicle changes following intense pulsed light axillary hair reduction: histometrical, histological and immunohistochemical evaluation
Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.