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Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.

The type of tumor suppressor gene lost affects the behavior of skin cancer.

The study found that p63 needs signals from morphogens to help skin cells differentiate properly.

Disrupting Bcl-xL in mice reduces skin cancer risk.

Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.

A pathway helps maintain long telomeres in both stem and cancer cells.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.

Over-expression of Sp2 can lead to cancer by preventing proper stem cell differentiation.

CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.

53BP1 focus analysis in hair cells can help estimate radiation doses.

Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.

HPV16-transformed cells can change human skin cell properties, aiding tumor growth.

Increasing PDCD4 protein may help prevent or treat some skin cancers.

HPV8 E6 gene causes growth of certain skin stem cells.

The risk of skin tumors becoming malignant depends on the specific skin cell type affected.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Overexpression of E2F1 can lead to skin tumors and disrupt hair growth.

Blocking mTORC1 reduces skin tumor growth in mice.

Polycomb Repressive Complex 1 is crucial for keeping stem cells stable and maintaining healthy adult tissues.

Krt15+ cells in mice can resist radiation, regenerate tissue, and start tumors, suggesting new cancer treatment targets.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.

Keratin 15 cells from hair follicles help develop and maintain skin tumors in mice.

Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.