research LPA-producing enzyme PA-PLA1α regulates hair follicle development by modulating EGFR signalling
The enzyme PA-PLA1α is important for proper hair follicle development.
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research The role of lysophosphatidic acid in the physiology and pathology of the skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6
p2y5, now called LPA6, is a receptor important for human hair growth.
research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
research A Missense Mutation within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis
A specific gene mutation causes woolly hair and hair loss.
research Autosomal Recessive Woolly Hair Caused by LIPH Mutations: A Case Series of Six Chinese Patients
LIPH mutations cause woolly hair in some Chinese people.
research Congenital hair loss disorders: Rare, but not too rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
research Diagnosis and treatment of isolated autosomal recessive woolly hair/hypotrichosis
ARWH is a rare hair disorder with no cure, but potential treatments include minoxidil and other therapies.
research Novel lysophosphoplipid receptors: their structure and function
Lysophospholipids can act as anti-inflammatory agents through specific receptors, but more research is needed.
research Genetic Hair Disorders: A Review
The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.
research The β9 Loop Domain of PA-PLA1α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis
A specific mutation in PA-PLA1α causes abnormal hair growth.
research Complete defect in PA-PLA1α secretion function leading to autosomal recessive woolly hair and hypotrichosis: insights from a novel compound heterozygous LIPH variant study in a Chinese pedigree
A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.
research LPA3, a unique G protein-coupled receptor for lysophosphatidic acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Hair graying and loss induced by imatinib mesylate
A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.
research Identification of factors contributing to phenotypic divergence via quantitative image analyses of autosomal recessive woolly hair/hypotrichosis with homozygous c.736T>ALIPH mutation
Different hair fiber development might explain why hair loss severity varies in patients with a specific genetic mutation, and treatments that thicken hair could help.
research Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6
LPAR6 has a unique way of binding and activating, which helps in designing treatments for hair loss and cancer.
research In Silico Characterization and Analysis of Clinically Significant Variants of Lipase-H (LIPH Gene) Protein Associated with Hypotrichosis
Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
research STEEL. IN: STRUCTURAL CONDITION ASSESSMENT
Targeting LPA could help treat skin disorders.
research Keratin 71 Mutations: From Water Dogs to Woolly Hair
A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
research Autotaxin–lysophosphatidic acid– LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways
LPA3 signaling in the uterus is crucial for placental formation and fetal development.
research SYSTEM ANALYSIS OF MECHANISMS OF EFFECT OF ESSENTIAL OILS
Essential oils can boost athletic performance by improving brain function and muscle relaxation.
research ЭКОЛОГИЧЕСКАЯ ТРИАДА ФАКТОРОВ ЗДОРОВЬЯ ЧЕЛОВЕКА: НЕГАТИВНЫЙ СОЧЕТАННЫЙ ЭФФЕКТ ФИЗИЧЕСКОЙ АКТИВНОСТИ, МАЛОПОДВИЖНОГО ПОВЕДЕНИЯ И COVID-19
Physical activity increased, but sedentary behavior also rose, especially in men.
research Ginseng and ginseng byproducts for skincare and skin health
Ginseng may improve skin health and anti-aging, but how it works is still unclear.
research ANALYSIS OF DC-POTENTIAL LEVEL IN ELDERLY PEOPLE WITH DIFFERENT LEVELS OF ANXIETY LIVING IN THE EUROPEAN NORTH OF RUSSIA
Elderly women in Northern Russia have higher anxiety and different brain energy patterns than men.
research ОСОБЕННОСТИ ДИНАМИКИ ПАРАМЕТРОВ НОСОВОГО ДЫХАНИЯ У ДЕТЕЙ С АДЕНОИДИТОМ
Measuring nasal breathing changes helps evaluate adenoiditis treatment in children.
research МИКРОБИОЦЕНОЗ ЛУНОК УДАЛЕННЫХ ЗУБОВ У ПАЦИЕНТОВ С АЛЬВЕОЛИТОМ
The collagen sponge with lincomycin heals tooth sockets faster and reduces infection better than iodoform gauze.
research МОДЕЛИРОВАНИЕ РИНОХИРУРГИЧЕСКИХ ВМЕШАТЕЛЬСТВ У КРЫС: ЭКСПРЕССИЯ БЕЛКА Р53 И ФОРМИРОВАНИЕ ТЕМНЫХ НЕЙРОНОВ В ГИППОКАМПЕ
p53 protein may help protect or kill neurons under stress.
research ОСТРЫЙ ПОСТОПЕРАЦИОННЫЙ БОЛЕВОЙ СИНДРОМ У ПАЦИЕНТОВ РИНОХИРУРГИЧЕСКОГО ПРОФИЛЯ ПОСЛЕ ИСПОЛЬЗОВАНИЯ ПОПУЛЯРНЫХ МЕТОДОВ АНЕСТЕЗИИ В Г. МОСКВЕ.
The anesthesia protocol with fentanyl and propofol caused the least pain during septoplasty.
research ОПЫТ ПРИМЕНЕНИЯ ФОТОБИОМОДУЛИРУЮЩЕЙ ТЕРАПИИ ДЛЯ УМЕНЬШЕНИЯ ИНТЕНСИВНОСТИ ОСТРОГО БОЛЕВОГО СИНДРОМА ПОСЛЕ СЕПТОПЛАСТИКИ
Photobiomodulation effectively reduces pain and stress after septoplasty.