research Alopecia Areata: An Update on Treatment Options for Children
Individualized treatment plans are crucial for children with alopecia areata, with promising options like JAK inhibitors showing significant hair regrowth.
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research The metabolic syndrome in children and adolescents
Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.
research Case 1: Severe acne – not just skin deep
Severe acne in a young girl may indicate underlying hormonal issues.
research Autoimmune disorders associated with type 1 diabetes: clinical overview and principles of management
Type 1 diabetes patients often have other autoimmune diseases, which complicate their care.
research ANDROGEN-DEPENDENT DERMOPATHY IN WOMEN WITH KELOID SCARS
Women with keloid scars often have acne and hair loss, especially those with "true" keloids, indicating a possible hormonal imbalance.
research ADRENOCORTICAL FUNCTION IN PUBERTY Serum ACTH, Cortisol and Dehydroepiandrosterone in Girls and Boys
Girls have higher DHEA levels earlier in puberty than boys, indicating earlier development.
research BENIGN PREMATURE ADRENARCHE: CLINICAL FEATURES AND SERUM STEROID LEVELS
Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.
research Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient
A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.
research Biotin deficiency in an infant fed with amino acid formula and hypoallergenic rice
Biotin should be added to Japanese amino acid formula to prevent deficiency.
research Severe kerion celsi due to Trichophyton mentagrophytes: a case report
Tinea capitis needs systemic treatment to avoid severe outcomes.
research Ocular aspects in biotinidase deficiency Clinical and genetic original studies
Early diagnosis and treatment of biotinidase deficiency are crucial to prevent vision problems.
research Dermatological changes in a prospective cohort of acutely ill, hospitalised Malawian children, stratified according to nutritional status
Skin changes were less common, and photo assessments were unreliable.
research Scalp Segmentation and Permanent Alopecia Prediction in Pediatric Craniospinal Irradiation: The PAST and HOPE Projects
The study focused on predicting permanent radiation-induced alopecia (RIA) in pediatric patients undergoing craniospinal irradiation (CSI) using the Pediatric Atlas-Based Scalp Segmentation Technique (PAST) and the Hair loss Outcome Prediction and Evaluation (HOPE) projects. Involving 48 pediatric patients, the study developed an atlas-based automated contouring protocol, achieving significant time efficiency and accuracy in scalp segmentation. Permanent RIA was observed in 45.8% of patients, with high-dose thiotepa and twice-daily fractionation identified as significant predictors. Dosimetric thresholds were established to aid in scalp-sparing CSI planning, highlighting the importance of radiation dose and treatment intensity in RIA development.
research Validation and Reference Ranges of Hair Cortisol Measurement in Healthy Children
Hair cortisol levels in children increase with age but are not affected by gender, puberty, or hair care.
research Intracrinology and The Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
research The SAHA Syndrome
SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
research The Hair Follicle: A Paradoxical Androgen Target Organ
Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
research Autoimmune Polyglandular Syndrome Type 1 in Russian Patients: Clinical Variants and Autoimmune Regulator Mutations
Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Primary Generalized Glucocorticoid Resistance and Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Apparent Cortisone Reductase Deficiency: A Rare Cause of Hyperandrogenemia and Hypercortisolism
Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.
research Hair‐thread tourniquet syndrome
A hair strand caused a rare case of limb strangulation in a teenage girl with autism, and the condition is not always linked to child abuse.
research Prevalence of Polycystic Ovary Syndrome in Girls Aged 14–18 Years in Isfahan, Iran
About 3% of high school girls aged 14-18 in Isfahan, Iran, have polycystic ovary syndrome.
research The influence of valproic acid treatment on hair and serum zinc levels and serum biotinidase activity
Valproic acid treatment may cause temporary hair loss due to reduced zinc and biotinidase levels, which tend to normalize after 6 months.
research Low-Dose Flutamide (125 mg/Day) as Maintenance Therapy in the Treatment of Hirsutism
Low-dose flutamide effectively maintains reduced hirsutism with no side effects.
research Association of Insulin Resistance with Hyperandrogenia in Women
Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
research The Molecular Basis of Androgen Insensitivity
Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
research Hair Cortisol Concentration in Healthy Children and Adolescents Is Related to Puberty, Age, Gender, and Body Mass Index
Hair cortisol levels in children are influenced by puberty, age, gender, and body mass index.
research A Girl with a Novel Splice Site Mutation in VDR Supports the Role of a Ligand-Independent VDR Function on Hair Cycling
A mutation in the VDR gene affects hair cycling without needing ligand binding.