46 citations
,
April 2021 in “International Journal of Molecular Sciences” Curcumin shows promise in reducing pain and inflammation, but more research is needed.
39 citations
,
January 2006 in “Journal of Cosmetic and Laser Therapy” Pneumatic Skin Flattening (PSF) significantly reduces pain during laser and IPL hair removal.
31 citations
,
June 2022 in “Journal of Yeungnam Medical Science” PRP may help reduce musculoskeletal pain, but its effectiveness is still uncertain.
13 citations
,
December 2010 in “Pharmacology Biochemistry and Behavior” Inhibiting certain enzymes made female rats more sensitive to low-level pain.
13 citations
,
April 2001 in “Journal of The American Academy of Dermatology” Using a vibrating device during injections can help reduce pain.
7 citations
,
December 2015 in “Turkish Journal of Osteoporosis” Vitamin D deficiency is common in adults with muscle and bone pain, especially women.
6 citations
,
February 2025 in “BMC Medical Research Methodology” Inconsistent safety reporting in chronic back pain trials risks patient safety and decision-making.
6 citations
,
January 2015 in “International Journal of Pediatrics and Adolescent Medicine” Hair removal cream effectively and painlessly treated infants with hair tourniquet syndrome.
5 citations
,
July 2020 in “Journal of Cosmetic Dermatology” A vibrating anesthetic device significantly reduces pain during mesotherapy for hair loss without complications.
4 citations
,
October 2022 in “Current Urology” Platelet-rich plasma shows promise in reducing pain for bladder pain syndrome.
4 citations
,
May 2019 in “Journal of Cosmetic Dermatology” Using a smaller syringe causes less pain when giving an injection.
3 citations
,
March 2024 in “Cureus” Platelet-Rich Plasma (PRP) helps reduce jaw pain and improve function in young adults with mild TMJ disorder.
2 citations
,
November 2024 in “Aesthetic Surgery Journal” Vibration anesthesia effectively and safely reduces pain during botulinum toxin injections.
2 citations
,
September 2024 in “Pharmaceuticals” Human placenta hydrolysate reduces inflammatory pain and nerve damage in mice.
2 citations
,
July 2009 in “Mayo Clinic Proceedings” A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.
2 citations
,
January 2003 in “Journal of Clinical Dermatology” 1 mg finasteride can cause reversible painful breast enlargement in men.
1 citations
,
June 2022 in “Al-Esraa University College journal for medical sciences.” Vitamin D supplements improve bone pain, tiredness, hair loss, and mood, especially in women and older adults.
1 citations
,
August 2014 in “Asian-Australasian Journal of Animal Sciences” Recombinant goat VEGF164 speeds up hair growth in mice.
December 2023 in “Frontiers in pharmacology” Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
Sphingosine 1-phosphate helps control mechanical pain.
October 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Using lidocaine before keloid injections makes the treatment more comfortable for patients.
May 2016 in “Mayo Clinic proceedings” A gluten-free diet fixed a man's severe stomach pain and bowel issue related to celiac disease, but not much his hair loss.
Botulinum toxin-A may increase hair growth and reduce hair loss in men with baldness, and injecting near blood vessels can improve pain relief and last longer.
Thoracic medial branch block may be a simpler and effective alternative to thoracic vertebroplasty for pain management.
June 2009 in “Mayo Clinic Proceedings” A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.
January 2026 in “National Science Review”
50 citations
,
May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
37 citations
,
December 2024 in “Theranostics” The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
3 citations
,
December 2022 in “The Neurologist” CARASIL, a rare genetic disorder, was confirmed in an Arabic woman, highlighting its rarity and need for stroke prevention.
3 citations
,
August 2021 in “Clinical Case Reports” Genetic testing is crucial before giving azathioprine to avoid severe side effects.