97 citations
,
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87 citations
,
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85 citations
,
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83 citations
,
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81 citations
,
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79 citations
,
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59 citations
,
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54 citations
,
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49 citations
,
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49 citations
,
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43 citations
,
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31 citations
,
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27 citations
,
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24 citations
,
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21 citations
,
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21 citations
,
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20 citations
,
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18 citations
,
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15 citations
,
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15 citations
,
January 2017 in “Polymers” Polyelectrolytes can improve cell surfaces for better medical applications.
13 citations
,
January 2023 in “Annual Review of Cancer Biology” Cancer risk is linked to the balance of mutations and environmental factors, not just the number of mutations.
12 citations
,
September 2024 in “MedComm” Bioprinting shows promise in medicine but needs collaboration to overcome challenges.
11 citations
,
December 2024 in “Wound Repair and Regeneration” The WRAHPS Guidelines standardize reporting in wound healing studies to improve research quality and therapy development.
11 citations
,
February 2011 in “International Journal of Molecular Sciences” Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.
10 citations
,
August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
10 citations
,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
9 citations
,
August 2024 in “Pharmacological Reviews” The intestinal lymphatic system is active and promising for targeted drug delivery and therapies.
9 citations
,
November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
8 citations
,
October 2024 in “Frontiers in Cell and Developmental Biology” Telocytes help organize male reproductive tissues and their changes can lead to diseases.
8 citations
,
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