A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.
Lower LDL-c levels predict higher COVID-19 mortality.
Clinical signs don't match inflammation levels in lichen planopilaris and frontal fibrosing alopecia.
March 2022 in “Brazilian Journal of Health Review” COVID-19 can cause a type of hair loss that usually starts 3-6 months after the illness, and treatment includes stress reduction and hair care products like Minoxidil.
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
Canine fetal hair follicle stem cells show pluripotency, with higher S100 protein expression at 40 days.
December 2015 in “Biomedical and biopharmaceutical research” Argan oil makes hair care products spread better and improves their texture.
December 2013 in “Biomedical and biopharmaceutical research” Nanotechnology shows promise for better drug delivery and cancer treatment.
Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.
September 2012 in “Medicina estética/Medicina estética” More research is needed to confirm if laser therapy effectively treats hair loss.
Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.
December 2020 in “Actas Dermo-Sifiliográficas” LLLT increases hair density and growth in AGA patients.
January 2018 in “Repositorio de Tesis - UNMSM” Physalis peruviana extract is more effective in treating benign prostatic hyperplasia in rats than finasteride and terazosine.
50 citations
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December 2017 in “Nanoscale” Polymeric micelle nanocarriers deliver adapalene more effectively to hair follicles than commercial products.
September 2015 in “Photodiagnosis and Photodynamic Therapy” January 1988 in “Toxicological Sciences” 4PeCDF is highly toxic to male rats, causing weight loss, organ damage, and death.
AnnoPharma effectively identifies substances causing adverse drug reactions in medical abstracts.
November 2022 in “Journal of Investigative Dermatology” A new molecule was found to be a safe and effective skin lightener and anti-aging product.
2 citations
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January 2018 in “Biomolecules & therapeutics” Polyamidoamine dendrimers can change the strength and direction of electroosmotic flow through the skin, affecting drug delivery.
21 citations
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June 2017 in “Journal of The American Academy of Dermatology” Topical DPCP is somewhat effective for hair loss in alopecia areata, but more research is needed.
November 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Restoring phenylalanine levels improved skin and hair symptoms in a PKU infant.
26 citations
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June 2003 in “PubMed” Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
May 2026 in “International Journal of Scientific Research in Chemistry” This study investigates the degradation profile of finasteride, a drug used for benign prostatic hyperplasia and androgenetic alopecia, under stress conditions. Using LC–MS, three degradation products were identified under acidic conditions, with minimal degradation in alkaline and oxidative environments. The degradation products were isolated and analyzed using preparative HPLC, HRMS, and NMR spectroscopy. The study revealed that the degradation process of DP-1 involved cleavage of the tert-butyl amide and addition of water across the alkene moiety. The structure of DP-1 was established through various spectroscopic techniques, and it, along with other degradation products, was found to be previously undescribed. These findings enhance the understanding of finasteride's degradation chemistry, aiding impurity profiling, stability studies, and quality control of its formulations.
1 citations
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July 2023 in “Biomimetics” A new hair treatment using a natural polyphenol complex improves hair strength, reduces static, and protects against UV damage.
37 citations
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September 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Diphencyprone (DPC) is an effective and safe long-term treatment for alopecia areata, especially with maintenance therapy.
18 citations
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January 2021 in “Theranostics” The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
2 citations
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January 2012 in “Journal of The Chilean Chemical Society” New method accurately measures finasteride in tablets and bulk.
July 2021 in “International journal of dermatology, venereology and leprosy sciences” Diphenylcyclopropenone is more effective and has fewer side effects than dinitrochlorobenzene for treating alopecia areata.
![Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)](/images/research/d743d32f-3115-48ff-9697-2f2d56130701/small/14175.jpg)
6 citations
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September 2015 in “Journal of Medicinal Chemistry” The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
September 2017 in “Journal of Investigative Dermatology” Photodynamic therapy can potentially remove nonpigmented hair by damaging hair follicles.