Lichen Planopilaris and Frontal Fibrosing Alopecia: Correlation of Clinical and Dermoscopic Findings with the Degree of Inflammation in Histopathological Examination

    August 2022
    Carolina Oliveira Costa Fechine
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    TLDR Clinical signs don't match inflammation levels in lichen planopilaris and frontal fibrosing alopecia.
    The study investigated the correlation between clinical and dermatoscopic findings with histopathological inflammation in 103 female patients with suspected lichen planopilaris (LPP) or frontal fibrosing alopecia (AFF). The results showed a significant discrepancy between clinical symptoms and dermatoscopic signs with the degree of histopathological inflammation. While pruritus and peripilar scaling were common symptoms, histopathology revealed more intense inflammation in AFF and deeper inflammation in LPP. However, clinical and dermatoscopic variables did not correlate with histopathological inflammation, indicating that these clinical parameters did not accurately reflect the inflammatory activity of LPP or AFF, impacting diagnosis and treatment strategies.
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