101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
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June 1992 in “Acta Histochemica” Human hair follicles have a unique cell distribution and differentiation pattern during growth.
133 citations
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March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
August 2015 in “PubMed Central” Epithelial-derived Pop-Up Keratinocytes (ePUKs) may enhance wound healing in regenerative medicine.
21 citations
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June 2004 in “Experimental Dermatology” Ber‐EP4 marks cells related to the secondary hair germ in hair follicles.
16 citations
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October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
23 citations
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September 2015 in “International Journal of Molecular Medicine” Activating ER-β, not ER-α, improves skin cell growth and wound healing.
November 2011 in “International Society of Hair Restoration Surgery” Keratins are key to developing and regenerating hair follicles for treating hair loss.
January 2007 in “Zhonghua shiyan waike zazhi” Basal layer skin cells help form the epidermis and hair follicles.
2 citations
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January 1989 in “The Nishinihon Journal of Dermatology” Seborrheic keratosis likely originates from the upper regions of hair follicles.
77 citations
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April 2005 in “Journal of Investigative Dermatology” Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
25 citations
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August 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
18 citations
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
November 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Keratin 79 cells help form and regenerate hair canals.
73 citations
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January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
26 citations
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May 2001 in “British Journal of Dermatology” Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.
7 citations
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April 2012 in “Biomolecular concepts” Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
25 citations
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October 2005 in “PubMed” Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
51 citations
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February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
120 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
4 citations
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January 1991 in “PubMed” Different bovine tissues show varying types of cytokeratins.
Dermal papilla cells can help form hair-like structures in lab-grown skin cells.
26 citations
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March 1995 in “Differentiation” A rabbit gene important for hair development was identified and detailed.
18 citations
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January 2018 in “Advances in experimental medicine and biology” Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
April 2017 in “Journal of Dermatological Science” Asymmetric hair follicle differentiation causes the unique shape of kinky hair.
33 citations
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August 2014 in “Veterinary Dermatology” Keratinocytes play a key role in skin health, but more research is needed.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.