April 2025 in “Cellular and Molecular Biology” Human dermal stem/progenitor cells can divide and differentiate more than hair follicle dermal papilla cells.
14 citations
,
January 2021 in “Stem cell research & therapy” Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
14 citations
,
March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.
2 citations
,
January 1989 Researchers developed a method to grow skin-like tissue from hair cells.
March 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Beard hair medulla cells have a unique and varied keratin pattern.
30 citations
,
November 1992 in “The Journal of Dermatology” Keratohyalin and trichohyalin proteins help form and organize skin and hair structures.
November 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Keratin 79 cells help form and regenerate hair canals.
421 citations
,
September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
5 citations
,
September 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
16 citations
,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
25 citations
,
August 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
September 2018 in “Apollo (University of Cambridge)” Translation levels actively determine keratinocyte cell fate.
130 citations
,
April 2003 in “Journal of Investigative Dermatology” Four specific keratins in hair follicles help understand hair structure and function.
April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
3 citations
,
September 2013 in “Bioscience Biotechnology and Biochemistry” Type II porcine hair keratin supports cell growth but hinders cell differentiation.
38 citations
,
July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
March 1995 in “The Journal of Dermatology” Immature hair cells can grow and change into different types of hair cells over time.
45 citations
,
February 2013 in “The Journal of Dermatology” Keratoacanthoma and some squamous cell carcinomas are linked to hair follicles, while others are not.
11 citations
,
April 1993 in “PubMed” Human hair cells can change based on their environment, especially interactions with certain skin cells.
292 citations
,
October 1985 in “The Journal of Cell Biology” Keratins and filaggrin change as fetal skin develops, marking key stages of skin formation.
January 2005 in “Australian viticulture” Different tissues in cows have different types of cytokeratins.
10 citations
,
August 2020 in “Current protocols in stem cell biology” Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
87 citations
,
September 2012 in “Journal of Cell Science” Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
175 citations
,
September 1998 in “British Journal of Dermatology” Keratin 17 gene mutations cause both steatocystoma multiplex and pachyonychia congenita type 2.
5 citations
,
September 2009 in “Acta Ophthalmologica” Hyper-keratinisation in Meibomian glands contributes to gland dysfunction.
36 citations
,
November 2019 in “Molecular biology and evolution” Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
19 citations
,
February 2013 in “Archives of Dermatological Research” 17 citations
,
January 2014 in “Journal of Oral and Maxillofacial Pathology” Seborrheic keratosis is a common, harmless skin growth that can look like cancer, so it may need a biopsy.
August 2021 in “Journal of Investigative Dermatology” Adjusting polyamine levels could help treat skin disorders like psoriasis and skin cancer.