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,
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,
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,
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,
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,
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67 citations
,
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64 citations
,
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61 citations
,
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59 citations
,
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55 citations
,
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54 citations
,
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54 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin A affects hair loss and immune response in alopecia areata.
50 citations
,
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50 citations
,
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49 citations
,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
49 citations
,
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48 citations
,
March 2021 in “Frontiers in Cell and Developmental Biology” Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.
47 citations
,
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46 citations
,
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45 citations
,
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44 citations
,
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36 citations
,
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33 citations
,
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30 citations
,
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29 citations
,
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27 citations
,
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27 citations
,
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25 citations
,
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24 citations
,
March 2024 in “Small Science” Single-cell encapsulation shows promise for medical use but faces production challenges.
24 citations
,
December 2023 in “Gels” 3D-printed hydrogels show promise in medicine but face challenges in resolution, cell viability, cost, and regulations.